Evidence map›Paper›PMID 41148639›Full record

ArticleInfectious disease reports2025

Cutaneous Leishmaniasis in the Immunocompromised: Diagnostic and Therapeutic Insights from a Case Documented in Central Italy.

Laura Povolo, Anna Barbiero, Michele Spinicci, Nicola Petrosillo, Alessandro Bartoloni, Lorenzo Zammarchi

Abstract readCase Reports
In one paragraph

Article in Infectious disease reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Laura PovoloDepartment of Experimental and Clinical Medicine, University of Florence, 50121 Florence, Italy.
Anna BarbieroDepartment of Experimental and Clinical Medicine, University of Florence, 50121 Florence, Italy.ORCID 0009-0004-4152-9346
Michele SpinicciDepartment of Experimental and Clinical Medicine, University of Florence, 50121 Florence, Italy.ORCID 0000-0002-5377-7118
Nicola PetrosilloInfection Prevention & Control/Infectious Disease Service, Fondazione Policlinico Universitario Campus Bio-Medico, 00128 Rome, Italy.ORCID 0000-0002-2585-7567
Alessandro BartoloniDepartment of Experimental and Clinical Medicine, University of Florence, 50121 Florence, Italy.ORCID 0000-0001-9758-1523
Lorenzo ZammarchiDepartment of Experimental and Clinical Medicine, University of Florence, 50121 Florence, Italy.ORCID 0000-0003-0892-8404

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCutaneous leishmaniasis (CL) poses a number of challenges when it comes to diagnosis and treatment, due to the variety of clinical presentations that mimic other conditions and hinder the choice of the most appropriate therapeutic approach, especially in the context of immunodepression. CASE PRESENTATION: We present the case of a 63-year-old woman on anti-tumor necrosis factor (TNF) therapy, who underwent surgical excision for the diagnostic purposes of a chronic non-healing lesion located on her right arm. The histopathological examination revealed the presence of

conclusionsThese results support the use of cutaneous swabs as a highly sensitive and less invasive tool for the diagnostic workup of CL. In addition, our case prompts a reflection on the management of immunosuppressed patients with CL, with particular emphasis on the risk of reactivation or simultaneous involvement of multiple anatomical sites, thus suggesting the need for specific considerations and personalized management for this group of subjects.

Indexed as

cutaneous leishmaniasiscutaneous swabimmunocompromisedItalyLeishmania infantumPCR

Identifiers

PMID41148639
PMCPMC12564556

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.