Evidence map›Paper›PMID 41148633›Full record

ArticleInfectious disease reports2025

Characterization of Carbapenem-Resistant Gram-Negative Bacilli Isolates in Multispecialty Private Hospitals in Lagos, Nigeria.

Moruf Salau, Uraiwan Kositanont, Pirom Noisumdaeng, Folasade Ogunsola, Abdul-Wahab Omo-Ope Ettu, Damilola Adewojo, Chinonso Ojimma, Omamode Ojomaikre, Kanjana Changkaew

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Article in Infectious disease reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Moruf SalauFaculty of Public Health, Thammasat University, Pathum Thani 12121, Thailand.ORCID 0009-0006-9109-9588
Uraiwan KositanontFaculty of Public Health, Thammasat University, Pathum Thani 12121, Thailand.
Pirom NoisumdaengFaculty of Public Health, Thammasat University, Pathum Thani 12121, Thailand.
Folasade OgunsolaDepartment of Medical Microbiology, University of Lagos, Lagos 101017, Nigeria.
Abdul-Wahab Omo-Ope EttuFaculty of Pathology, National Postgraduate Medical College of Nigeria, Lagos 102004, Nigeria.
Damilola AdewojoDepartment of Medical Microbiology Laboratory, R-Jolad Hospital, Lagos 100242, Nigeria.
Chinonso OjimmaDepartment of Medical Microbiology Laboratory, Havana Specialist Hospital, Lagos 10001, Nigeria.
Omamode OjomaikreDepartment of General Outpatient, Lagoon Hospitals, Lagos 101000, Nigeria.
Kanjana ChangkaewFaculty of Public Health, Thammasat University, Pathum Thani 12121, Thailand.ORCID 0000-0003-3883-3430

Funding

Faculty of Public Health, Thammasat University
6 · The paper itself

Abstract

BACKGROUND/

objectivesCarbapenem-resistant Gram-negative bacilli (CR-GNB) pose a growing challenge to public health worldwide due to limited treatment options. This cross-sectional study investigated the characteristics of CR-GNB isolated from clinical specimens in Lagos, Nigeria.

methodsGram-negative bacilli (GNB) and clinical data were obtained from three multi-specialist private hospitals between March and June 2023. The GNB were identified using the Analytical Profile Index (API) and investigated for CR-GNB by disk diffusion. Antimicrobial resistance patterns and carbapenemase gene data for presumptive carbapenemase-producing Gram-negative bacilli (CP-GNB) were analyzed using Vitek-2 and polymerase chain reaction (PCR).

resultsOf 317 GNB, 29.0% (n = 92) were CR-GNB. Significantly higher numbers of CR-GNB were reported from the intensive care unit and oncology department (

conclusionsEmerging CR-GNB, specifically CP-GNB, in Nigeria emphasize the need for specific therapeutic management of infected patients. Antimicrobial stewardship and long-term surveillance efforts must be implemented in healthcare settings, as well as improved, accelerated microorganism identification techniques.

Indexed as

carbapenem-resistant Gram-negative bacilli (CR-GNB)public healthtreatment options

Identifiers

PMID41148633
PMCPMC12562451

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