Evidence map›Paper›PMID 41148609›Full record

ArticleAsian Pacific journal of cancer prevention : APJCP2025

The Determining of Pesticide Residue Levels in Children Diagnosed with Acute Leukemia in Cukurova Region, Turkiye.

Sema Yilmaz, Nebile Daglioglu, Nihal Inandiklioglu, Asli Atasoy Aydin, Ismail Ethem Goren, Serhan Kupeli, Ayse Ozkan, Goksel Leblebisatan, Begul Yagci Kupeli, Gulay Sezgin and 3 more

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Article in Asian Pacific journal of cancer prevention : APJCP, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Sema YilmazKocaeli City Hospital, Department of Pediatric Hematology and Oncology, Izmit, Turkiye.ORCID 0000-0003-4277-3880
Nebile DagliogluAnkara University, Institute of Forensic Sciences, Department of Forensic Toxicology, Ankara, Turkiye.
Nihal InandikliogluBozok University Faculty of Medicine, Department of Medical Biology, Yozgat, Turkiye.
Asli Atasoy AydinAnkara University, Institute of Forensic Sciences, Department of Forensic Toxicology, Ankara, Turkiye.
Ismail Ethem GorenAnkara University, Institute of Forensic Sciences, Department of Forensic Toxicology, Ankara, Turkiye.
Serhan KupeliCukurova University Faculty of Medicine, Department of Pediatric Hematology and Oncology, Adana, Turkiye.
Ayse OzkanCukurova University Faculty of Medicine, Department of Pediatric Hematology and Oncology, Adana, Turkiye.
Goksel LeblebisatanCukurova University Faculty of Medicine, Department of Pediatric Hematology and Oncology, Adana, Turkiye.
Begul Yagci KupeliUniversity of Health Sciences, Ankara City Hospital, Department of Pediatric Hematology and Oncology, Adana, Turkiye.
Gulay SezginCukurova University Faculty of Medicine, Department of Pediatric Hematology and Oncology, Adana, Turkiye.
Nihal BozCukurova University Faculty of Medicine, Department of Pediatric Hematology and Oncology, Adana, Turkiye.
Adnan BarutcuCukurova University Faculty of Medicine, Department of Pediatric Hematology and Oncology, Adana, Turkiye.ORCID 0000-0001-8930-1122
Ibrahim BayramCukurova University Faculty of Medicine, Department of Pediatric Hematology and Oncology, Adana, Turkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute lymphoblastic leukemia (ALL) is the most common childhood malignancy. in children. Children can be exposed to pesticides during pregnancy or by their parent carried out pesticides to home. The objective of this study was to study pesticide residues in both acute leukemia patients and healthy children.

methodsTwenty nine patients with acute leukemia [22 boys (76%) and 7 girls (24%)] and 33 healthy children [(19 boys (57%), 14 girls (43%)] were included in the study. We analyzed eight PCB (PCB 28, PCB 52, PCB 101, PCB 118, PCB 138, PCB 153, PCB 180 and PCB 202), HCB, three HCH isomers, 4,4'-DDT, 4,4'-DDD and 4,4'-DDE were investigated in bone marrow of newly diagnosed acute leukemia patients and peripheral blood samples of healthy children.

resultsThe most detectable OCPs were β-HCH, δ-HCH and PCB28, triflumizole and thiometon were commonly found as OPPs. The significant difference was found statistically between ALL cases and control group according to the residues of PCB28 (74,06±85,29), β-HCH (72,06±89,07) and δ-HCH (23,35±42,93) (p=0.001). Additionally, OPPs consisted triflumizole (7,23±9,17), thiometon (3,37±4,30) and halfenprox (1,90±3,22) showed distinctive difference statistically (p=0.001).

conclusionPesticide residues were estimated significantly in bone marrow of leukemia patients should be considered an important for public health with the decreasing or preventing of pesticide exposure which have a role in leukemia ethiology.

Indexed as

Environmental ExposurePesticide ResiduesPrecursor Cell Lymphoblastic Leukemia-LymphomaAdolescentCase-Control StudiesChildChild, PreschoolFemaleFollow-Up StudiesHumansInfantMalePesticidesPolychlorinated BiphenylsPrognosisTurkeyPesticide ResiduesPesticidesPolychlorinated BiphenylschildrenLeukemiaorganochlorineorganophosphoruspesticide

Identifiers

PMID41148609
PMCPMC12905808

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.