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ArticleDrugs - real world outcomes2025

Outcomes and Usability of Formoterol-Budesonide Delivered Through Synchrobreathe

Santhalingam Balamurugan, Himanshu Pophale, Utsav Samariya, Komalkirti Apte, Sheetu Singh, Raja Dhar, Sujeet Rajan, Rajesh Swarnakar, Deepak Talwar, Meena Lopez and 5 more

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Article in Drugs - real world outcomes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

15 authors.

Santhalingam BalamuruganA.C.S Medical College and Hospital, Chennai, Tamil Nadu, India.
Himanshu PophaleShreyas Hospital, Pune, Maharashtra, India.
Utsav SamariyaChest Clinic, Uttar Pradesh, Varanasi, India.
Komalkirti ApteExcellentia Consulting Services, Pune, Maharashtra, India.
Sheetu SinghRajasthan Hospital, Jaipur, Rajasthan, India.
Raja DharCMRI CK Birla Hospital-Kolkata, Kolkata, West Bengal, India.
Sujeet RajanBhatia Hospital-Mumbai, Mumbai, Maharashtra, India.
Rajesh SwarnakarGetwell Hospital and Research Institute, Nagpur, Maharashtra, India.
Deepak TalwarMetro Hospital and Heart Institute, New Delhi, Delhi, India.
Meena LopezMedical Affairs, Cipla Ltd., Mumbai, Maharashtra, India.
Vaishali NaikMedical Affairs, Cipla Ltd., Mumbai, Maharashtra, India. Vaishali.naik@cipla.com.
Sandesh SawantMedical Affairs, Cipla Ltd., Mumbai, Maharashtra, India.
Sushmeeta ChhowalaMedical Affairs, Cipla Ltd., Mumbai, Maharashtra, India.
Abhijit VaidyaMedical Affairs, Cipla Ltd., Mumbai, Maharashtra, India.
Jaideep GogtayMedical Affairs, Cipla Ltd., Mumbai, Maharashtra, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic obstructive pulmonary disease (COPD) is a significant public health concern, and inhalation therapy is a critical component of its management. However, using an inhaler is challenging, especially for patients with COPD, who are often elderly and experience reduced dexterity, visual and cognitive impairment, and difficulty synchronizing inhalation with dose actuation. Synchrobreathe

methodsThis prospective, multicenter, observational study carried out during August 2021 and August 2022 evaluated the clinical outcomes of the budesonide/formoterol combination (BUD/FORM) delivered through Synchrobreathe

resultsIn the study population (N = 250), significant reductions from baseline were observed in mean CAT (-6.56 ± 0.33; p < 0.001) and mBDS (-1.60 ± 0.09; p < 0.0001) scores at 12 weeks. Almost all (98%) patients were satisfied with Synchrobreathe

conclusionBUD/FORM delivered through Synchrobreathe

Identifiers

PMID41148565
PMCPMC12634959

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