Observational studyJournal of clinical monitoring and computing2025
The predictive value of perfusion indices in the triage and clinical management of carbon monoxide poisoning.
Observational study in Journal of clinical monitoring and computing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Arterial blood gas analysis in risk stratification of acute carbon monoxide poisoning.The Indian journal of medical research · 2026Article
Corrections and comments
- Erratum issued
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTraditional assessments using carboxyhemoglobin (COHb) levels alone often do not adequately predict clinical course of carbon monoxide (CO) poisoning cases. Perfusion index (PI) and pleth variability index (PVI) offer non-invasive, continuous monitoring of peripheral perfusion, potentially improving patient management. The objective of this study is to evaluate whether perfusion indices can assist in triage and monitoring of patients with CO poisoning.
methodsAll patients aged 18 years and older, diagnosed with CO poisoning were consecutively enrolled in this prospective observational study from January 2019 to May 2023. Perfusion indices, COHb and lactate levels were measured at diagnosis (values denoted by 1) and after 60-min hyperbaric or normobaric oxygen therapy (HBOT or NBOT) (values denoted by 2).
resultsPI-1 showed significant moderate negative correlation with COHb-1 levels in all patients and AUC value of PI-1 in predicting the necessity for HBOT was 0.935. Patients requiring HBOT had significantly lower PI-1 and higher COHb-1, lactate-1, and PVI-1 compared to those receiving NBOT. Following treatment, PI increased, and PVI, lactate, and COHb decreased significantly in both treatment groups (p<0.001 for all).
conclusionsPerfusion indices, especially PI, may reflect changes in COHb levels and could provide additional information to support triage and monitoring in CO poisoning.
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