ArticleInternational ophthalmology2025
Clinical characteristics and antibiotic susceptibility patterns of bacterial keratitis in the South of Vietnam.
Article in International ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInfectious keratitis is a major cause of corneal blindness, with bacterial keratitis particularly prevalent in tropical, agriculture-dominant regions such as Southern Vietnam. PURPOSES: To identify the demographic characteristics, risk factors, clinical features, and antibiotic susceptibility patterns of bacteria isolated from patients with corneal ulceration.
methodsA case series was conducted involving patients who presented to the Cornea Department of Ho Chi Minh City Eye Hospital between November 2020 and October 2021.
resultsA total of ninety-nine cases of bacterial keratitis were documented. The mean age of the patients was 48.2 ± 15.3 years. Most participants were male, and the majority were cultivators (30.3%). Meibomian gland dysfunction was the most frequent predisposing factor (57.6%), followed by ocular trauma (52.5%) and diabetes mellitus (16.2%). The mean duration from symptom onset to presentation was 4.1 ± 3.1 days; however, patients with Pseudomonas aeruginosa keratitis presented significantly earlier (2.8 ± 1.6 days) than those with other bacterial infections. The most commonly isolated organisms were coagulase-negative Staphylococcus (57.6%) and Pseudomonas aeruginosa (21.2%). Staphylococcus spp. keratitis was significantly associated with peripheral infiltration, shallow stromal involvement, and absence of hypopyon. In contrast, Pseudomonas aeruginosa keratitis was strongly associated with eyelid edema, conjunctival edema, central infiltration, deep stromal involvement, stromal melting, ring infiltrate, retrocorneal plaque, hypopyon > 1 mm, and fibrin formation in the anterior chamber. The majority of coagulase-negative Staphylococcus isolates were susceptible to vancomycin (90-100%). Pseudomonas aeruginosa isolates were highly susceptible to tobramycin (100%) and levofloxacin (95.0%), whereas none were susceptible to moxifloxacin. The proportions of multidrug-resistant isolates among coagulase-negative Staphylococcus and Pseudomonas aeruginosa were 68.4% and 85.7%, respectively.
conclusionMultidrug-resistant strains among coagulase-negative Staphylococcus and Pseudomonas aeruginosa were notably prevalent. Our study provides valuable insights into the clinical and microbiological patterns of bacterial keratitis, which guide antibiotic selection and management.
Indexed as
Identifiers
41148536What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.