ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2026
Seasonal trends, clinical outcomes, and viral coinfections of human metapneumovirus infections in Mexican children from 2021 to 2024.
Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
Abstract
purposeHuman Metapneumovirus (hMPV) is a respiratory pathogen of global concern, particularly in paediatric populations. To gain a better understanding of hMPV infection in children, this study analysed the seasonal distribution, clinical characteristics, and epidemiological relevance of hMPV among Mexican children from 2021 to 2024.
methodsA retrospective analysis was performed on 10,513 nasopharyngeal swabs collected from symptomatic paediatric patients. hMPV was detected using a multiplex PCR-based assay. Positive cases were stratified by age, disease severity, comorbidities, and viral coinfections. Descriptive and inferential statistical analyses were conducted to evaluate the demographic, clinical, and microbiological characteristics of paediatric patients infected with hMPV, stratified by disease severity and comorbidity profiles.
resultsA total of 753 samples (7.2%) were positive for hMPV. Peaks occurred in autumn 2023 and spring 2023-2024. Among 639 cases with clinical data, children under two years old were more likely to either present moderate to severe illness (69.0%) and be hospitalised compared to older children (OR = 2.91, 95% CI: 1.18-6.85, p = 0.016). While common comorbidities were unrelated to severity, certain chronic conditions showed significant associations (OR = 3.98, 95% CI: 2.19-7.85, p < 0.001). Coinfections, particularly with Rhinovirus/Enterovirus, were prevalent in moderate cases (20.0%; p = 0.011) and showed a borderline association with increased risk of hospitalisation (OR = 1.53, 95% CI: 1.00-2.40, p = 0.057).
conclusionshMPV can cause significant disease in young or medically complex children, underscoring the need for ongoing surveillance and clinical vigilance in Mexican paediatric health systems and other countries with a high number of respiratory diseases.
Indexed as
Identifiers
41148509What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.