SynthesisOdontology2026
The effect of bioceramic materials on dentin formation and their use to protect the dentin-pulp complex-a systematic review and meta-analysis.
Synthesis in Odontology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This systematic review aims to promote a systematic search of the literature to provide relevant information for the clinical choice of bioceramic material for the protection of the dentin-pulp complex, as well as to stimulate new projects and research aimed at expanding knowledge about its characteristics and benefits. The objective was to answer the following question: "Do bioceramic materials act on dentin formation and can they be used to protect the dentin-pulp complex?". This systematic review followed the PRISMA guidelines and was registered in PROSPERO. A customized search strategy was applied in five databases and in the gray literature. The selection of articles was performed independently by two reviewers in two stages, based on eligibility criteria. Inclusion: Randomized or non-randomized clinical studies that used bioceramics for pulp protection and evaluated dentin tissue formation. Exclusion: Literature reviews, book chapters, in vivo/in vitro studies, theses and articles that did not evaluate dentin formation by bioceramics. Risk of bias was assessed using ROBINS-I (for non-randomized studies) and ROB 2 (for randomized trials). The meta-analysis was performed using Review Manager Web, and GRADE was used to assess the certainty of the evidence. A total of 147 potential studies were found, 117 were evaluated based on their titles and abstracts, and 7 were selected for full-text review. Of these, 5 were included in this systematic review. The five articles included presented a low overall risk of bias. Qualitative and quantitative analyses suggested that bioceramic material, when compared to control groups, presented greater thickness and quality of the dentin bridge, greater inflammation, but lower values of pulp necrosis, as confirmed by meta-analysis. Thus, the question posed by this systematic review was answered, since the bioceramic materials evaluated act on dentin formation and can be used to protect the dentin-pulp complex.
Indexed as
Identifiers
41148418What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.