Evidence map›Paper›PMID 41148370›Full record

ArticleLangenbeck's archives of surgery2025

Etiologic factors in developing sacrococcygeal pilonidal sinus disease in males; A cased-control study.

Jochem de Kort, A Akke Pronk, Marijke R van Dijk, Annemiek Maaskant, Menno R Vriens, Niels Smakman, Edgar J B Furnee

Abstract read
In one paragraph

Article in Langenbeck's archives of surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. [Research on deep learning-based pathological image classification of pilonidal sinus].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jochem de KortDepartment of Surgery, Diakonessenhuis Utrecht, P.O. Box 80250, 3508 TG, Utrecht, the Netherlands. jdkort1@diakhuis.nl.
A Akke PronkDepartment of Urology, Radboud University Medical Centre, Nijmegen, the Netherlands.
Marijke R van DijkDepartment of Pathology, University Medical Centre Utrecht, Utrecht, the Netherlands.
Annemiek MaaskantAnimal Science Department Biomedical Primate Research Centre, Rijswijk, the Netherlands.
Menno R VriensDepartment of surgery, University Medical Centre Utrecht, Utrecht, the Netherlands.
Niels SmakmanDepartment of Surgery, Diakonessenhuis Utrecht, P.O. Box 80250, 3508 TG, Utrecht, the Netherlands.
Edgar J B FurneeDepartment of Surgery, University Medical Centre Groningen, Groningen, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTwo main theories have been proposed for the development of sacrococcygeal pilonidal sinus disease (SPSD), but the exact etiology remains unclear. Better understanding of etiologic factors could improve insight into the disease and help prevent both primary and recurrent pilonidal sinus disease. This study aimed to identify etiologic factors in the development of pilonidal sinus disease.

methodFor this case control study, potential etiologic factors such as family history of SPSD, BMI, working in a sitting position, and smoking were evaluated in 83 patients with primary SPSD and 83 controls. Additionally, anatomical factors, including the depth, width, and hair density of the natal cleft were compared. Lastly, microscopic hair analysis assessed hair characteristics such as thickness, pigmentation, breakage, hair cuticle irregularities and hair thickness irregularities.

resultsPatients with SPSD were significantly more often smokers and had a family history of SPSD. They also had a significantly shallower and wider natal cleft, a greater number of hairs in the natal cleft, and these hairs were significantly thicker with more cuticle and thickness irregularities compared to the controls. However, after multivariable analysis, only working in a sitting position, a shallower natal cleft and more hairs at the natal cleft were independently associated with SPSD.

conclusionA shallower natal cleft, more hair at the natal cleft and working in a sitting position were independent etiologic factors of SPSD. Therefore, keeping the natal cleft free of hair and avoiding prolonged sitting position should be recommended as preventive measures when counselling patients with SPSD.

Indexed as

Pilonidal SinusAdultCase-Control StudiesHairHumansMaleMiddle AgedRisk FactorsSacrococcygeal RegionSmokingYoung AdultBenign surgeryEtiologyPilonidal sinus diseaseProctology

Identifiers

PMID41148370
PMCPMC12568826

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.