Evidence map›Paper›PMID 41148355›Full record

ArticleEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2025

Adolescent trauma and alcohol: increased risk for severe head injury and organ dysfunction-insights from the TraumaRegister DGU

Jason-Alexander Hörauf, Jan-Niklas Franz, Ramona Sturm, Rolf Lefering, Borna Relja, Ingo Marzi, Nils Wagner, TraumaRegister Dgu

Abstract read
In one paragraph

Article in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jason-Alexander Hörauf *Department of Trauma Surgery and Orthopedics, University Hospital Frankfurt, Goethe-University, Frankfurt am Main, Germany. hoerauf@med.uni-frankfurt.de.
Jan-Niklas Franz *Department of Trauma Surgery and Orthopedics, University Hospital Frankfurt, Goethe-University, Frankfurt am Main, Germany.
Ramona SturmDepartment of Trauma Surgery and Orthopedics, University Hospital Frankfurt, Goethe-University, Frankfurt am Main, Germany.
Rolf LeferingInstitute for Research in Operative Medicine (IFOM), University Witten/Herdecke, Cologne, Germany.
Borna ReljaDepartment of Trauma, Hand, Plastic and Reconstructive Surgery, Translational and Experimental Trauma Research, University Ulm, Ulm, Germany.
Ingo MarziDepartment of Trauma Surgery and Orthopedics, University Hospital Frankfurt, Goethe-University, Frankfurt am Main, Germany.
Nils WagnerDepartment of Trauma Surgery and Orthopedics, University Hospital Frankfurt, Goethe-University, Frankfurt am Main, Germany.
TraumaRegister DguCommittee on Emergency Medicine, Intensive Care and Trauma Management (Sektion NIS) of the German Trauma Society (DGU), Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAlcohol consumption is common among young individuals and is a significant, yet preventable, risk factor for injuries and fatalities. In adults, it influences injury patterns, severity, and potentially outcomes via immunomodulatory effects. However, data in adolescents are scarce. This study seeks to address this deficiency by analyzing data from the TraumaRegister DGU

methodsThis retrospective TR-DGU analysis included trauma patients aged 10-20 years admitted between 2015 and 2019. Patients were stratified by blood alcohol level (BAL positive vs. negative) and analyzed for demographics, injury patterns, prehospital characteristics, and in-hospital outcomes, including ICU length of stay (LOS), organ failure, and mortality.

resultsOf 1,823 patients, 1,481 were BAL- and 324 BAL+. Alcohol-positive incidence increased over the study period, particularly in older adolescents, and was more frequent in winter, on weekends, and at night. BAL + patients were more often involved in violent and penetrating trauma and sustained more severe head injuries (43.6% vs. 36.5%, p = 0.016) but were intubated less often (30.8% vs. 34.5%, p = 0.099), significantly so in the 18-20-year group. BAL + adolescents had higher rates of respiratory organ failure (15.2% vs. 8.3%, p = 0.014) and sepsis (5.9% vs. 2.8%, p = 0.03), with no significant differences in ICU LOS or mortality.

conclusionAlcohol use remains a significant factor among adolescent trauma patients in German-speaking countries. As trauma mechanisms vary by age, targeted prevention strategies are crucial. Intoxicated adolescent trauma patients form a high-risk group requiring special attention. Further research into alcohol's immunomodulatory effects in this population is essential to improve trauma care strategies.

Indexed as

Alcohol DrinkingCraniocerebral TraumaMultiple Organ FailureAdolescentBlood Alcohol ContentChildFemaleGermanyHospital MortalityHumansInjury Severity ScoreIntensive Care UnitsLength of StayMaleRegistriesRetrospective StudiesBlood Alcohol ContentAdolescent traumaAlcoholInjury severityTrauma patients

Identifiers

PMID41148355
PMCPMC12568830

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.