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ArticleEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2025

High trauma mortality and severe injury burden in Pakistan: epidemiology, surgical interventions, and in-hospital care from a digital hospital-based trauma registry.

Natasha Shaukat, Muhammad Bazil Musharraf, Komal Abdul Rahim, Asma Altaf Hussain Merchant, Tanweer Ahmad, Huba Atiq, Uzma Rahim Khan, NadeemUllah Khan, Saima Mushtaq, Junaid Razzak and 1 more

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Article in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Natasha ShaukatDepartment of Epidemiology, Robert Stempel College of Public Health and Social Work, Florida International University, Miami, FL, USA.
Muhammad Bazil MusharrafCentre of Excellence for Trauma and Emergencies, Aga Khan University, Karachi, Pakistan.
Komal Abdul RahimCentre of Excellence for Trauma and Emergencies, Aga Khan University, Karachi, Pakistan.
Asma Altaf Hussain MerchantMedical College, Aga Khan University, Karachi, Pakistan.
Tanweer AhmadDepartment of Neurosurgery, Jinnah Postgraduate Medical Centre, Karachi, Sindh, Pakistan.
Huba AtiqCentre of Excellence for Trauma and Emergencies, Aga Khan University, Karachi, Pakistan. Huba.atiq@aku.edu.
Uzma Rahim KhanDepartment of Emergency Medicine, Aga Khan University Hospital, Karachi, Pakistan.
NadeemUllah KhanDepartment of Emergency Medicine, Aga Khan University Hospital, Karachi, Pakistan.
Saima MushtaqDepartment of Emergency Medicine, Jinnah Postgraduate Medical Centre, Karachi, Sindh, Pakistan.
Junaid RazzakCentre of Excellence for Trauma and Emergencies, Aga Khan University, Karachi, Pakistan.
Adil HaiderMedical College, Aga Khan University, Karachi, Pakistan.

Funding

Fogarty International Center of the National Institutes of Health Award Number D43TW007292
6 · The paper itself

Abstract

backgroundLow- and middle-income countries (LMICs) face a high burden of trauma-related deaths, yet lack prospective, standardized data to guide care. In Pakistan, in-hospital trauma management and outcomes remain poorly documented. PURPOSE: The aim of this study was to examine injury epidemiology, post-emergency department care, and hospital outcomes using a pilot digital trauma registry in Pakistan.

methodsThis study was conducted from December 2021 to February 2023 at two leading tertiary care hospitals in Karachi, Pakistan. We included all admitted adult trauma patients (≥ 18 years). We prospectively collected data on demographics, injury details, inter-hospital case management, in-hospital care, and discharge outcomes.

resultsA total of 3,087 patients were enrolled, mostly male (79.82%), with 24.33% under 25 years old and 42.38% of Muhajir ethnicity. Road traffic injuries (RTIs) (56.43%), primarily amongst riders of two-wheelers (56.74%), were the leading cause, of whom only 8.66% wore helmets. Most arrived by ambulance (77.12%), and one third (33.66%) were transferred from another hospital. Extremity (55.17%) and head/neck injuries (41.72%) were most common. Severe injuries (ISS > 15) were seen in 30.26%, while 90.86% had a GCS > 12. X-rays (92.81%), CT scans (56.04%), and ultrasounds (16.55%) were common investigations. Surgery was performed in 50.28% of cases. The in-hospital mortality rate was 15.10%, and the median length of stay (LOS) was five days.

conclusionOur findings show high in-hospital trauma mortality, often among patients transferred from other facilities, emphasizing the role of timely care. This study highlights the potential of trauma registries to inform preventive policies and clinical care, particularly in low-income settings.

Indexed as

Wounds and InjuriesAccidents, TrafficAdolescentAdultFemaleHospital MortalityHumansInjury Severity ScoreLength of StayMaleMiddle AgedPakistanRegistriesYoung AdultEpidemiologyIn-hospital mortalityInjuriesTrauma registry

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.