ReviewAnalytical and bioanalytical chemistry2026
From conventional to miniaturized workflows: a critical review of sample preparation methods for nonsteroidal anti-inflammatory drug analysis.
Review in Analytical and bioanalytical chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Review
- Preparation of Gemini-Functionalized Cellulose Paper Sorptive Phases for Enrichment of Non-Steroidal Anti-Inflammatory Drugs in Water.Journal of separation science · 2026Article
- Plug-and-play coaxial nested-tube supported liquid membrane extraction for the determination of nonsteroidal anti-inflammatory drugs in human plasma.RSC advances · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Non-steroidal anti-inflammatory drugs (NSAIDs) are extensively used pharmaceuticals that persist in biological fluids, environmental waters, and food, raising concerns for therapeutic monitoring, drug quality control, and ecological safety. Because trace-level detection is strongly dictated by pretreatment, recent research has shifted from conventional liquid-liquid extraction and solid-phase extraction toward miniaturized, greener, and automation-ready formats. Liquid-phase microextraction variants (e.g., DLLME, HF-LPME, EME, SALLE) and solid-phase microextraction methods (SPME, MEPS, DSPE, MSPE, QuEChERS) have demonstrated reduced solvent consumption, improved enrichment, and greater compatibility with complex matrices. Advanced sorbent materials, nanostructures, and hybrid designs offer enhanced selectivity but often face challenges of scalability, cost, and genuine sustainability. This review critically evaluates these approaches in terms of principles, performance, and limitations, highlighting trends in miniaturization, automation, and appliable metrics. The aim is to provide analytical scientists with a balanced perspective to guide matrix- and purpose-driven selection of NSAID extraction methods and to outline future directions toward standardized, high-throughput, and environmentally sustainable workflows.
Indexed as
Identifiers
41148262What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.