Evidence map›Paper›PMID 41148243›Full record

ReviewKidney3602026

Current State of Live and Deceased Donor Kidney Transplantation in India: Challenges and Opportunities.

Vivek Kute, Georgi Abraham, Swarnalata Guditi, N V Seethalekshmy, Dolly Daniel, Priscilla Rupali, Arpita Lahiri, Narayan Prasad, Pranjal Kashiv, Sanjay P Kolte and 2 more

Abstract readReview
In one paragraph

Review in Kidney360, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Vivek KuteDepartment of Nephrology, Institute of Kidney Diseases and Research Center, Dr. H.L. Trivedi Institute of Transplantation Sciences, Ahmedabad, India.
Georgi AbrahamDepartment of Nephrology, Madras Medical Mission, Tanker Foundation, Chennai, India.ORCID 0000-0002-6957-2432
Swarnalata GuditiDepartment of Pathology, Amrita Institute of Medical Sciences, Kochi, India.ORCID 0000-0002-0777-7811
N V SeethalekshmyDepartment of Immunology, Christian Medical College, Vellore, India.ORCID 0000-0003-2393-9013
Dolly DanielDepartment of Infectious Disease, Christian Medical College, Vellore, India.
Priscilla RupaliDepartment of Infectious Disease, Christian Medical College, Vellore, India.ORCID 0000-0002-5115-067
Arpita LahiriDepartment of Nephrology, Institute of Post Graduate Medical Education Research, Kolkata, India.
Narayan PrasadDepartment of Nephrology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.ORCID 0000-0001-9801-0474
Pranjal KashivDepartment of Nephrology, Saraswati Kidney Care Center, Nagpur, India.
Sanjay P KolteDepartment of Urology, Sparsh Urology and Kidney Hospital, Nagpur, India.ORCID 0009-0008-5728-037
Sunil ShroffMOHAN Foundation, Chennai, India.
Manish BalwaniDepartment of Nephrology, Saraswati Kidney Care Center, Nagpur, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

India continues to face a significant gap between organ demand and supply, primarily because of low deceased organ donation rates and limited public awareness. The deceased donor rate remains 0.77 per million population, contributing to only 15% of transplants, with only anecdotal reports of donation after circulatory death. By contrast, living donor transplants have increased to 9.4 per million population. Globally, India ranks first in living donor transplants, third in total transplants, and 68th in deceased donor transplants. A total of 682 kidney transplant centers are registered under the National Organ and Tissue Transplant Organization (NOTTO), with a predominant concentration in the private sector (87%) and only 13% in government hospitals. Gender disparities in transplantation remain striking, underpinned by long-standing socioeconomic and cultural inequities. Between 2019 and 2023, female recipients constituted only 30% of all living donor kidney transplants, although women represented 66.2% of donors. The overall proportion of female recipients rose modestly from 28% in 2019 to 36.8% in 2023. Globally, men accounted for 64% of all recipients, with India ranked 59th among 78 countries for male dominance among living donors. Infrastructural limitations persist, with nearly 80% of immunology laboratories in metropolitan areas. Access to transplant pathology, infectious disease specialists, and advanced diagnostics remains sparse in tier 2 and 3 cities. Policy reforms-including amendments to the Transplantation of Human Organs and Tissues Act, establishment of State and Regional Organ and Tissue Transplant Organizations, and centralized coordination by NOTTO-aim to enhance access and equity. The NOTTO Chintan Shivir 2024 emphasized digital registries and protocol standardization. Although innovations such as ABO blood group (ABO)-incompatible and multicenter kidney-paired donation are advancing, broader systemic reforms are essential for long-term equity and sustainability.

Indexed as

Kidney TransplantationLiving DonorsTissue and Organ ProcurementTissue DonorsFemaleHealthcare DisparitiesHumansIndiaMaletransplantation

Identifiers

PMID41148243
PMCPMC13134797

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.