Evidence map›Paper›PMID 41148109›Full record

ArticleTechnology in cancer research & treatment

Abbreviated MRI Screening in Turkish Women Aged 40-69 With Dense Breasts: A Prospective Feasibility Study.

Inci Kizildag Yirgin, Neslihan Cabioglu, Memduh Dursun, Omur Can Tasci, Aziz Şener, Gulcin Vatandaş, Gonul Aykuter, Ravza Yilmaz, Ayse Nilufer Ozaydin, Sibel Ozkan Gurdal and 5 more

Abstract read
In one paragraph

Article in Technology in cancer research & treatment. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Inci Kizildag YirginDepartment of Radiology. Oncology Institute, Istanbul University, Istanbul, Turkey.ORCID 0000-0003-0563-5964
Neslihan CabiogluDepartment of General Surgery, Istanbul University, School of Medicine, Istanbul, Turkey.
Memduh DursunDepartment of Radiology, Istanbul University, School of Medicine, Istanbul, Turkey.
Omur Can TasciBahçeşehir Breast Cancer Screening Center, İstanbul, Turkey.
Aziz Şenerthe Department of General Surgery, Kanuni Sultan Süleyman Training and Research Hospital, İstanbul, Turkey.
Gulcin VatandaşBahçeşehir Breast Cancer Screening Center, İstanbul, Turkey.
Gonul AykuterBahçeşehir Breast Cancer Screening Center, İstanbul, Turkey.
Ravza YilmazDepartment of Radiology, Istanbul University, School of Medicine, Istanbul, Turkey.
Ayse Nilufer OzaydinDepartment of Public Health, Marmara University School of Medicine, Istanbul, Turkey.
Sibel Ozkan GurdalDepartment of General Surgery Namik Kemal University, School of Medicine, Tekirdag, Turkey.
Beyza OzcinarDepartment of General Surgery, Istanbul University, School of Medicine, Istanbul, Turkey.
Nuran AkyurtSchool of Health Services, Department of Medical Services and Techniques Marmara University, Istanbul, Turkey.
Vahit OzmenDepartment of General Surgery, Istanbul University, School of Medicine, Istanbul, Turkey.
Arda KayhanDepartment of Radiology, Kanuni Sultan Süleyman Training and Research Hospital, Istanbul, Turkey.
Erkin AribalDepartment of Radiology, Acibadem M.A.A University school of medicine, Istanbul, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

IntroductionWe aimed to investigate the feasibility of abbreviated protocol (AP) breast magnetic resonance imaging (MRI) screening in women with dense breasts in a screening program in a middle-income country.MethodsThis prospective study included 649 women selected randomly from 1285 women with type C and D breasts in a screening program, of which 238 underwent an abbreviated breast MRI screening (AP-MRI). The AP-MRI consisted of dynamic series during the first and second post-contrast phases, in addition to axial T1W and axial T2W-fat sat (TRIM) sequences. The reference standard for the study was based on pathology results obtained from biopsies and normal screening mammography results within two years.ResultsMRI scans of 201 women (84.4%) displayed normal or benign findings (BIRADS-1 and 2). An additional 25 women (10.5%) were recommended for MRI or ultrasound (USG) follow-up (BI-RADS-3) and did not show any progression in the two-year follow-up. The remaining 12 women (5%) were recommended a biopsy (BIRADS-4), of which five were reclassified as BIRADS-3 after a second-look ultrasound. Subsequently, a biopsy of the remaining seven patients did not reveal any malignancies. They all had a negative two-year follow-up. The main challenges encountered were scheduling AP-MRI screening and compliance of women.ConclusionIn this small, single-center cohort of women with dense breasts, supplemental AP MRI screening did not identify additional cancers and was associated with false-positive findings that could lead to overdiagnosis and unnecessary biopsies. Larger, prospective, multicenter studies are needed to clarify the role of AP MRI in breast cancer screening and to determine its optimal integration into existing screening programs.

Indexed as

BreastBreast DensityBreast NeoplasmsEarly Detection of CancerMagnetic Resonance ImagingAdultAgedFeasibility StudiesFemaleHumansMammographyMass ScreeningMiddle AgedProspective StudiesTurkeybreastbreast densitymammographyneoplasmsradiology

Identifiers

PMID41148109
PMCPMC12576089

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.