ReviewInvestigative ophthalmology & visual science2025
Location and Identity of Photoreceptors Contributing to the Full-Field Stimulus Test (FST).
Review in Investigative ophthalmology & visual science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
4 authors.
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Abstract
Quantification of visual function in severe forms of inherited retinal disease is challenging because of lack of stable gaze. Full-field stimulus test (FST) was developed two decades ago as an outcome measure to evaluate potential changes to the vision after gene augmentation therapy in RPE65-associated Leber congenital amaurosis. With greater use, there has been greater interest in better understanding photoreceptors dominating the perception of FST. Review of the literature and currently available data support the longstanding and currently prevailing hypothesis that sensitivity of the healthiest retinal region beneficial to visual function drives the sensitivity of FST. In contrast, the alternative hypothesis-that far peripheral photoreceptors hidden from the visual field signal perception of intraocularly scattered light originating from FST-is not supported.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.