Evidence map›Paper›PMID 41147459›Full record

ArticleClinical chemistry and laboratory medicine2026

Small-scale external quality assessment of methylated

Chengxiang Chu, Xiaoyu Fan, Chunli Shi, Ran Zhao, Yingwei Chen, Xiaobo Hu, Xueliang Wang

Abstract read
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Article in Clinical chemistry and laboratory medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chengxiang ChuDepartment of Quality Control Material R&D, 608229 Shanghai Center for Clinical Laboratory , Shanghai, China.
Xiaoyu FanDepartment of Molecular Biology, Shanghai Center for Clinical Laboratory, Shanghai, China.ORCID https://orcid.org/0000-0002-0390-5871
Chunli ShiDepartment of Molecular Biology, Shanghai Center for Clinical Laboratory, Shanghai, China.
Ran ZhaoDepartment of Quality Control Material R&D, 608229 Shanghai Center for Clinical Laboratory , Shanghai, China.
Yingwei ChenDepartment of Quality Control Material R&D, 608229 Shanghai Center for Clinical Laboratory , Shanghai, China.
Xiaobo HuDepartment of Quality Control Material R&D, 608229 Shanghai Center for Clinical Laboratory , Shanghai, China.
Xueliang WangDepartment of Quality Control Material R&D, 608229 Shanghai Center for Clinical Laboratory , Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesDNA methylation in short homeobox gene 2 (

methodsA sample panel was prepared containing two

resultsThe sample panel demonstrated sufficient stability and applicability. Results were collected from 21 laboratories in 2023 and 29 laboratories in 2024. Approximately 90.5 % (19/21) and 75.9 % (22/29) laboratories achieved correct results in 2023 and 2024, respectively. Out of the 105 results in 2023 and 145 results in 2024, 1 false negative and 3 false positives were observed in 2023 and 6 false negatives and 12 false positives in 2024.

conclusionsThis two-round EQA study in China emphasizes the need for improvement in the performance of

Indexed as

DNA MethylationHomeodomain ProteinsTumor Suppressor ProteinsChinaHumansLung NeoplasmsQuality ControlHomeodomain ProteinsRASSF1 protein, humanSHOX2 protein, humanTumor Suppressor Proteinsexternal quality assessmentlung cancermethylation detectionquality managementRASSF1ASHOX2

Identifiers

PMID41147459

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.