Evidence map›Paper›PMID 41147410›Full record

ArticleJournal of the American Heart Association2025

Procedural Volume and Outcomes in Lower-Extremity Peripheral Vascular Interventions: Insights From the NCDR Peripheral Vascular Intervention Registry.

Zainali Chunawala, Arman Qamar, Kevin Kennedy, Neil Keshvani, Ambarish Pandey, Dharam J Kumbhani, Cheong Jun Lee, Gregory Mishkel, Eric Secemsky, Deepak L Bhatt

Abstract readMulticenter Study
In one paragraph

Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zainali ChunawalaDivision of Cardiology University of Texas Southwestern Medical Center Dallas TX USA.ORCID 0000-0002-7288-7435
Arman QamarEndeavor Center for Cardiovascular Intervention Outcomes Research and Evaluation (ECCORE), Section of Interventional Cardiology & Vascular Medicine Endeavor Health Cardiovascular Institute Glenview IL USA.ORCID 0000-0003-0607-1240
Kevin KennedySaint Luke's Mid America Heart Institute Kansas City MO USA.
Neil KeshvaniDivision of Cardiology University of Texas Southwestern Medical Center Dallas TX USA.ORCID 0000-0001-6890-8670
Ambarish PandeyDivision of Cardiology University of Texas Southwestern Medical Center Dallas TX USA.ORCID 0000-0001-9651-3836
Dharam J KumbhaniDivision of Cardiology University of Texas Southwestern Medical Center Dallas TX USA.ORCID 0000-0003-4321-4538
Cheong Jun LeeDepartment of Vascular Surgery NorthShore University Health System Evanston IL USA.
Gregory MishkelEndeavor Center for Cardiovascular Intervention Outcomes Research and Evaluation (ECCORE), Section of Interventional Cardiology & Vascular Medicine Endeavor Health Cardiovascular Institute Glenview IL USA.
Eric SecemskyDivision of Cardiology, Department of Medicine Beth Israel Deaconess Medical Center Boston MA USA.ORCID 0000-0003-3861-3163
Deepak L BhattMount Sinai Fuster Heart Hospital Icahn School of Medicine at Mount Sinai New York NY USA.ORCID 0000-0002-1278-6245

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLower-extremity peripheral vascular interventions (PVIs) are increasingly used for treatment of peripheral artery disease. However, the relationship between hospital and operator PVI volume with in-hospital major adverse limb events (MALEs) and major adverse cardiovascular events (MACEs) is not well established.

methodsWe used the NCDR PVI (National Cardiovascular Data Registry) registry, including procedural data from April 1, 2014, to December 31, 2019, assessing in-hospital MALEs and MACEs during hospitalization for PVI. Annualized PVI volumes were categorized on the basis of operator or site volume. Generalized linear mixed models assessed volume-outcome relationships after adjustment of covariates.

resultsBetween 2014 and 2019, 55 785 PVI procedures were performed at 97 hospitals by 555 operators. Adjusted analysis showed no statistically significant association between hospital volume and MALEs (highest versus lowest volume: odds ratio, 0.91 [95% CI, 0.74-1.11];

conclusionsIn contemporary practice, a significant relationship was observed between operator volume and adjusted PVI outcomes. Highest-volume operators had lower rates of in-hospital MALEs and MACEs compared with lowest-volume operators.

Indexed as

Endovascular ProceduresHospitals, High-VolumeHospitals, Low-VolumeLower ExtremityPeripheral Arterial DiseaseAgedAged, 80 and overFemaleHumansMaleMiddle AgedRegistriesRisk AssessmentRisk FactorsTreatment OutcomeUnited Statesmajor adverse cardiovascular eventsmajor adverse limb eventsperipheral artery diseaseperipheral vascular interventions

Identifiers

PMID41147410
PMCPMC12684603

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.