ArticleJournal of oral rehabilitation2026
Root-Filled Teeth With and Without Pain in a Cohort of Individuals Scheduled for Regular Dental Check-Ups. A Matched Case-Control Study.
Article in Journal of oral rehabilitation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 authors.
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Abstract
backgroundAn overwhelming majority of root-filled teeth are asymptomatic, despite commonly exhibiting radiological signs of apical periodontitis (AP). When symptoms prevail, several sources are conceivable. This case-control study investigates underlying causes of pain from root-filled teeth.
objectivesThe aims were to (i) compare painful root-filled teeth with root-filled teeth without pain matched on sex, age, jaw and tooth type, and (ii) explore patient- and tooth-related factors that may explain the pain.
methodsAdult participants (≥ 20 years) with root-filled teeth were investigated through anamnestic, clinical and radiographic examinations. Analyses compared painful to pain-free teeth statistically, and possible origins of pain were indicated. Clinical data and periapical radiographs were used to identify the presence of AP.
resultsTenderness to percussion and apical palpation, probing depth ≥ 6 mm, swelling and apical radiolucency (p = 0.002-0.040) were more common with painful teeth, while density and length of root filling, unfilled canals, fracture of root and positive screening for TMD (3Q/TMD) did not differ between groups (p = 0.074-0.63). Among the 55 symptomatic teeth, AP was identified in 48 with varying diagnostic certainty. Indication of temporomandibular disorder (TMD) was present in 15 teeth, and marginal periodontitis (MP) in eight teeth. For six teeth, none of the three conditions could be identified.
conclusionsTenderness to percussion and apical palpation, swelling, pocket depth ≥ 6 mm, and apical radiolucency were more common with painful teeth. The pain was most frequently associated with AP, but pain due to TMD and MP may occur. For 10% of the root-filled teeth, no findings could explain the symptoms.
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