ReviewChembiochem : a European journal of chemical biology2025
Method Overview for Discovering ATE1 Substrates and their Arginylation Sites.
Review in Chembiochem : a European journal of chemical biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Review
- Method Overview for Discovering ATE1 Substrates and their Arginylation Sites.Chembiochem : a European journal of chemical biology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Arginylation is a protein modification event in which cellular machinery recognizes a conserved N-terminal or side-chain motif and post-translationally installs an arginine residue to signal a protein for degradation. This modification affects protein function, stability, and half-life and is essential to proper functions in mammalian systems. Since its discovery in the early 1960s, scientists have struggled to broadly characterize this modification in its canonical function outside of a handful of specific cases. It is known to be an essential cellular mark, as loss of the installation enzyme is embryonically lethal. However, the discovery of the substrates regulated by this mark has been slow and has required some creativity by the scientists who have chased it. Over the course of roughly six decades, the library of substrates has consistently grown through various applications. Here, we seek to summarize all approaches that have been applied to discovering and studying arginylation.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.