ArticleJournal of inflammation research2025
Ineffective Recanalization and Complications in Patients with Acute Ischemic Stroke Receiving Endovascular Treatment: Predictive Value of the c-Reactive Protein-Albumin-Lymphocyte (CALLY) Index.
Article in Journal of inflammation research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prognostic value of the CALLY index for functional outcomes in acute ischemic stroke: a systematic review and exploratory quantitative synthesis.Frontiers in neurology · 2026Pooled it
- Prognostic impact of the C-reactive protein-albumin-lymphocyte index in patients with resected lung cancer associated with interstitial pneumonia.Surgery today · 2026Article
- Association between prognostic nutritional index and mortality in patients with sepsis-associated delirium: a retrospective cohort study using the MIMIC-IV database.BMC nutrition · 2026Article
- Prognostic Value of the C-Reactive Protein-Albumin-Lymphocyte (CALLY) Index for In-Hospital Mortality in Spontaneous Intracerebral Hemorrhage: A Comparative Analysis with Hematoma Volume.Journal of inflammation research · 2026Article
- Association of the C-reactive protein-albumin-lymphocyte index with clinical outcomes after mechanical thrombectomy for acute ischemic stroke.Frontiers in aging neuroscience · 2026Article
- Relationship between high-sensitivity C-reactive protein/lymphocyte ratio and post-thrombolysis short-term outcome in acute ischemic stroke patients.Frontiers in aging neuroscience · 2026Article
- Preoperative C-Reactive Protein-Albumin-Lymphocyte (CALLY) Score and the Risk of Acute Kidney Injury Following Cardiac Surgery: A Retrospective Cohort Study.Journal of inflammation research · 2026Article
- Earlier endovascular therapy within 24 h of ischemic stroke is associated with attenuated systemic inflammation and better neurological recovery.Frontiers in neurologyArticle
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: The C-reactive protein-albumin-lymphocyte (CALLY) index, as a composite biomarker reflecting nutritional reserves and immunosuppression, has demonstrated important predictive value in various disease. We aimed to investigate the CALLY index's predictive value versus previous inflammatory-nutritional biomarker for ineffective recanalization and complications in acute ischemic stroke (AIS) patients who received emergency endovascular therapy (EVT). Methods: We retrospectively reviewed 705 AIS patients admitted to Nanfang Hospital for EVT from January 2019 to December 2023. We calculated the CALLY index, Geriatric Nutritional Risk Index, Controlling Nutritional Status score, Prognostic Nutritional Index, and C-reactive protein-to-albumin ratio, and assessed their predictive significance for ineffective recanalization using univariate and multivariate logistic regression. Predictive efficacy was compared via receiver operating characteristic (ROC) curve analysis, while the Net Reclassification Improvement (NRI) and Integrated Discrimination Improvement (IDI) quantified the incremental value of models incorporating these biomarkers. In addition, we explored the relationship between the CALLY index and post-EVT complications. Results: The CALLY index had the best predictive validity with an area under the ROC curve of 0.73. The new model incorporating the CALLY index had the best optimization effect (NRI of 0.157, P=0.028; IDI of 0.029, P=0.008). A significant correlation was also shown between the CALLY index and stroke-associated pneumonia. Conclusion: The CALLY Index demonstrated its potential as an innovative and accessible indicator for prognosis.
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