Evidence map›Paper›PMID 41146918›Full record

ArticleInternational journal of cardiology. Cardiovascular risk and prevention2025

Cardiac rehabilitation for outpatients aged over 80 years with cardiovascular diseases.

Ryoko Someya, Yasushi Matsuzawa, Yoshitaka Shimizu, Hidefumi Nakahashi, Masaaki Konishi, Eiichi Akiyama, Yohei Hanajima, Hisaya Kondo, Tomohiro Yoshii, Ryosuke Sato and 4 more

Abstract read
In one paragraph

Article in International journal of cardiology. Cardiovascular risk and prevention, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Ryoko SomeyaDepartment of Rehabilitation, Yokohama City University Medical Center, Yokohama, Japan.
Yasushi MatsuzawaDepartment of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.
Yoshitaka ShimizuDepartment of Rehabilitation, Yokohama City University Medical Center, Yokohama, Japan.
Hidefumi NakahashiDivision of Cardiology, Yokohama City University Medical Center, Yokohama, Japan.
Masaaki KonishiDepartment of Medical Science and Cardiorenal Medicine, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Eiichi AkiyamaKawaguchi Cardiovascular and Respiratory Hospital, Saitama, Japan.
Yohei HanajimaDivision of Cardiology, Yokohama City University Medical Center, Yokohama, Japan.
Hisaya KondoDivision of Cardiology, Yokohama City University Medical Center, Yokohama, Japan.
Tomohiro YoshiiDivision of Cardiology, Yokohama City University Medical Center, Yokohama, Japan.
Ryosuke SatoDivision of Cardiology, Yokohama City University Medical Center, Yokohama, Japan.
Kazuko HayashiDepartment of Rehabilitation, Yokohama City University Medical Center, Yokohama, Japan.
Kozo OkadaDivision of Cardiology, Yokohama City University Medical Center, Yokohama, Japan.
Teruyasu SuganoDivision of Cardiology, Yokohama City University Medical Center, Yokohama, Japan.
Kiyoshi HibiDivision of Cardiology, Yokohama City University Medical Center, Yokohama, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Japan had the highest proportion of the elderly in the world, with one in 10 individuals aged ≥80 years. Consequently, the number of patients with cardiovascular diseases is increasing. Older patients often have comorbidities such as frailty, sarcopenia, and cognitive decline that leads to a decreased quality of life (QOL). We analyzed the effects of outpatient cardiac rehabilitation (OCR) in elderly patients with cardiovascular disease. Methods: The comprehensive OCR had been provided by a multidisciplinary team. We analyzed data from 49 patients with cardiovascular diseases, aged ≥80 years, who received cardiopulmonary exercise (CPX) tests based OCR. Frailty, physical function, QOL, exercise tolerance, and vascular endothelial function were assessed before and after OCR. Results: All 49 patients had completed the OCR program. The mean patients' age was 84.1 ± 3.6 years and 32.7 % were male. The proportion of frailty and pre-frailty participants significantly decreased from 92 % to 67 % following OCR. The QOL (KCCQ: 76.8 ± 18.4 vs. 81.4 ± 20.4; P = 0.0196), exercise tolerance (peak VO Conclusions: The comprehensive OCR with CPX-based exercise therapy and the multidisciplinary approach significantly improved frailty, the QOL, physical function, exercise tolerance, and vascular endothelial function in patients with cardiovascular diseases aged ≥80 years.

Indexed as

Cardiac rehabilitationCardiopulmonary exercise testCardiovascular diseaseElderlyFrailtyVascular endothelial function

Identifiers

PMID41146918
PMCPMC12554074

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.