ArticleAmerican heart journal plus : cardiology research and practice2025
Association of physical activity and sedentary behavior with stages of cardiovascular-kidney-metabolic syndrome among U.S. adults: NHANES 2007-2020.
Article in American heart journal plus : cardiology research and practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Associations of Physical Activity With Mortality Across Cardiovascular-Kidney-Metabolic Syndrome Stages: Evidence From NHANES 1999 to 2018.Journal of the American Heart Association · 2026Article
- Association between physical activity and cardiovascular-kidney-metabolic syndrome in older Chinese adults: a nationwide, cross-sectional study.Journal of global health · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Cardiovascular-kidney-metabolic (CKM) syndrome, newly defined by the American Heart Association, integrates metabolic risk factors, chronic kidney disease, and cardiovascular dysfunction. Although clinically important, evidence-based prevention strategies remain limited. This study examined associations of moderate-to-vigorous physical activity (MVPA) and sedentary behavior (SB) with CKM stage in a representative U.S. adult sample. Methods: We used survey-weighted multinomial logistic regression and restricted cubic splines (RCS). MVPA was classified as 0, 1-149, and ≥ 150 min/week; SB as <5, 5-8, and ≥ 8 h/day; CKM was staged 0-4 (stage 0 as reference). Predefined subgroups were age (20-59 vs 60-79 years), sex (female vs male) and PIR (high >3.49; medium >1.49-<3.49; low ≤1.49). Results: Compared with individuals reporting no MVPA, those achieving ≥150 min/week had approximately 33 % lower odds of CKM stage 1 (OR 0.67, 95 % CI 0.46-0.97), 44 % lower odds of stage 2 (OR 0.56, 95 % CI 0.38-0.83), 92 % lower odds of stage 3 (OR 0.09, 95 % CI 0.02-0.32), and 65 % lower odds of stage 4 (OR 0.35, 95 % CI 0.19-0.63). Subgroup analyses by age, sex, poverty-income ratio, and SB indicated that the protective impact of MVPA was evident across age and socioeconomic subgroups, with relatively stronger associations among younger adults and benefits at both low and high socioeconomic strata. By contrast, SB showed weaker independent associations with CKM severity after full adjustment. Conclusions: Greater MVPA was associated with lower odds of advanced CKM stage. These findings highlight the role of physical activity in CKM prevention and support public health strategies to reduce lifestyle-related risks.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.