ArticleCureus2025
Papillary Thyroid Carcinoma in a Branchial Cleft Cyst: A Two-Case Single-Center Experience.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Papillary thyroid carcinoma (PTC) arising within a branchial cleft cyst (BCC) is an exceptionally rare condition that presents diagnostic and therapeutic challenges. This study aims to describe two such cases identified in our institution and to review the relevant literature. A retrospective review of the pathology database of Unidade Local de Saúde (ULS) de Coimbra in Coimbra, Portugal, from 2015 to the present identified two such cases. Clinical, pathological, and follow-up data were analyzed, and a brief literature review was performed. The first patient, a 63-year-old man, presented with a right lateral cervical cystic mass that was surgically excised and found to be a papillary carcinoma. Subsequent total thyroidectomy revealed a microscopic focus of papillary carcinoma in the thyroid, and he received adjuvant radioactive iodine, remaining disease-free to date. The second patient, a 43-year-old man, underwent excision of a right lateral cervical BCC, with histology confirming papillary carcinoma arising within the cyst. Further evaluation demonstrated a synchronous 12 mm PTC with nodal involvement, treated with total thyroidectomy, neck dissection, and radioactive iodine, with no evidence of recurrence on follow-up. These findings highlight the need to consider malignant transformation in BCCs and underscore the importance of thorough histopathological assessment of lateral neck masses.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.