ReviewCureus2025
Role of Combined Ortho-Plastic Approaches in the Reconstruction of Gustilo-Anderson Grade III Upper Limb Injuries: A Systematic Review.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This systematic review investigates the role of combined ortho-plastic approaches in the reconstruction of Gustilo-Anderson Grade III upper limb fractures, which are characterized by severe soft tissue damage, contamination, and high rates of complications such as infection and nonunion. A total of five studies, encompassing 196 patients, were analyzed following a systematic search across PubMed, Embase, Scopus, and the Cochrane Library in accordance with PRISMA 2020 guidelines. The included studies evaluated early multidisciplinary interventions involving orthopedic fixation and plastic surgical soft tissue reconstruction. Early intervention, particularly within 72 hours was associated with improved outcomes, including limb salvage rates up to 100%, reduced deep infection rates as low as 2.4%, and union rates up to 84.3%. Both single-stage and staged procedures showed positive results, with vascularized flap coverage playing a crucial role in maintaining tissue viability and promoting bone healing. The findings strongly support the use of coordinated ortho-plastic strategies to manage complex upper limb trauma, although further prospective, high-quality trials are needed to standardize timing and techniques.
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Registered trials
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