Evidence map›Paper›PMID 41146671›Full record

ArticleMaterials today. Bio2025

Dual-function hemoglobin-encapsulating ZIF-8 nanoparticles: Oxygen transport capability and carbonic anhydrase-like activity.

Ana María Pablo-Sainz-Ezquerra, Marta Rubio-Huertas, Ege Tini Tunca, Peter Waaben Thulstrup, Leticia Hosta-Rigau

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials today. Bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ana María Pablo-Sainz-EzquerraDepartment of Health Technology, Technical University of Denmark, Nils Koppels Allé, Building 423, 2800, Kgs. Lyngby, Denmark.
Marta Rubio-HuertasDepartment of Health Technology, Technical University of Denmark, Nils Koppels Allé, Building 423, 2800, Kgs. Lyngby, Denmark.
Ege Tini TuncaDepartment of Health Technology, Technical University of Denmark, Nils Koppels Allé, Building 423, 2800, Kgs. Lyngby, Denmark.
Peter Waaben ThulstrupDepartment of Chemistry, University of Copenhagen, Universitetsparken 5, 2100, Copenhagen, Denmark.
Leticia Hosta-RigauDepartment of Health Technology, Technical University of Denmark, Nils Koppels Allé, Building 423, 2800, Kgs. Lyngby, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hemoglobin-based oxygen carriers (HBOCs) have emerged as a promising alternative to red blood cell (RBC) transfusions, addressing key limitations such as cold storage requirements, restricted availability of universal donor blood, and the need for cross-matching, which collectively hinder their immediate use in emergency settings. Despite their potential, existing HBOCs primarily focus on oxygen delivery while overlooking a crucial physiological function of native RBCs: carbon dioxide (CO

Indexed as

Blood substitutesCarbonic anhydraseHemoglobin-based oxygen carriersMetal-organic frameworksNanozymesZIF-8

Identifiers

PMID41146671
PMCPMC12554216

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.