Evidence map›Paper›PMID 41146648›Full record

ArticleJournal of pain research2025

Concurrent Validity of the Operationalization of High-Impact Pain Construct in the Health and Retirement Study.

Javier A Tamargo, Yenisel Cruz-Almeida

Abstract read
In one paragraph

Article in Journal of pain research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Javier A TamargoPain Research and Intervention Center of Excellence, University of Florida, Gainesville, FL, USA.ORCID 0000-0001-9385-9049
Yenisel Cruz-AlmeidaPain Research and Intervention Center of Excellence, University of Florida, Gainesville, FL, USA.ORCID 0000-0002-0065-0236

Funding

HRS Yrs29-34: Y33 SSA CoFundingU01AG009740 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Jessica Faul, KENNETH M LANGA · 1990 to 2026
$555.8M
Supplement-Discovery and Validation of Epigenetic Biomarkers in Brain TissueR01AG067757 · NIA · UNIVERSITY OF FLORIDA · PI CRUZ-ALMEIDA, YENISEL · 2020 to 2024
$4.2M
the Integrative and Multidisciplinary Pain and Aging Research Training (IMPART) ProgramT32AG049673 · NIA · UNIVERSITY OF FLORIDA · PI FILLINGIM, ROGER B · 2015 to 2024
$3.2M
Diversity Supplement for Kristina Bell: Biopsychosocial pain predictors of mobility decline in agingR01AG076082 · NIA · UNIVERSITY OF FLORIDA · PI Stephen Coombes, Yenisel Cruz-Almeida · 2022 to 2026
$3.1M
Mechanisms of Oxytocin's Analgesia in Older Adults (Diversity Supplement)R01AG059809 · NIA · UNIVERSITY OF FLORIDA · PI CRUZ-ALMEIDA, YENISEL, EBNER, NATALIE C · 2018 to 2022
$1.8M
NIA NIH HHS L32 AG096730NIA NIH HHS R01 AG059809NIA NIH HHS R01 AG067757NIA NIH HHS R01 AG076082NIA NIH HHS T32 AG049673NIA NIH HHS U01 AG009740
6 · The paper itself

Abstract

Purpose: Chronic pain epidemiology is hindered by inconsistent definitions and methods. The US National Pain Strategy introduced high-impact chronic pain as a pain surveillance standard, defined as chronic pain that interferes with work or life activities. This study aimed to validate the operationalization of high-impact pain in the Health and Retirement Study (HRS), a large, nationally representative cohort of older adults. Patients and Methods: We analyzed data from the 2010 HRS pain module. High-impact pain was operationalized with two questions that have been fielded in the HRS since its inception. Pain intensity and pain-related disability were assessed using numeric rating scales and the Pain Disability Index (PDI). We used Wilcoxon rank-sum tests and logistic regressions to compare high- versus low-impact pain. Pain impact was also assessed at a 2-year follow-up in 2012. Results: Out of 508 participants, 335 (65.9%) reported high-impact pain. Those with high-impact pain had significantly higher pain-related disability (median PDI: 48 [33, 60] vs 19 [8, 36], P<0.0001), average pain intensity (median: 6 [4, 8] vs 5 [3, 6], P<0.0001) and were more likely to report chronic (OR: 1.75 [95% CI: 1.19, 2.58]) and constant (OR: 3.09 [1.93, 4.93]) pain. High-impact pain was associated with a relative risk of 1.80 (1.53, 2.11) for continued high-impact pain at a 2-year follow-up. Conclusion: The HRS operationalization of high-impact pain demonstrates strong concurrent validity with established measures of pain disability, intensity, and impact. The HRS provides a valuable tool for advancing pain research, particularly in aging populations.

Indexed as

epidemiologygerosciencepain

Identifiers

PMID41146648
PMCPMC12554259

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.