Evidence map›Paper›PMID 41146536›Full record

ArticleEchocardiography (Mount Kisco, N.Y.)2025

Cross-Sectional Association of Ground-Level Ozone and Nitrogen Dioxide With Cardiac Mechanics Using Speckle-Tracking Echocardiography in the Cardiovascular Health Study.

Andrew Y Chang, Joel D Kaufman, Sanjiv J Shah, Annabel Xulin Tan, Ravi B Patel, Helene G Margolis, Bruce M Psaty, Julius M Gardin, Sadeer Al-Kindi, Thomas R Austin and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Echocardiography (Mount Kisco, N.Y.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Andrew Y ChangSection of Cardiovascular Medicine, Department of Medicine, Yale University, New Haven, Connecticut, USA.ORCID 0000-0002-3009-6678
Joel D KaufmanDepartment of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington, USA.
Sanjiv J ShahDivision of Cardiology, Department of Medicine and Bluhm Cardiovascular Institute, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.ORCID 0000-0002-5655-8201
Annabel Xulin TanDepartment of Epidemiology and Population Health, Stanford University, Stanford, California, USA.
Ravi B PatelDivision of Cardiology, Department of Medicine and Bluhm Cardiovascular Institute, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Helene G MargolisDepartment of Internal Medicine, School of Medicine, University of California Davis, Sacramento, California, USA.
Bruce M PsatyCardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, USA.
Julius M GardinDivision of Cardiology, Department of Medicine, Rutgers New Jersey Medical School, Newark, New Jersey, USA.
Sadeer Al-KindiDepartment of Cardiology, Houston Methodist Hospital, Houston, Texas, USA.
Thomas R AustinDepartment of Epidemiology, University of Washington, Seattle, Washington, USA.
Michelle L BellYale Center On Climate Change and Health, Yale School of Public Health, New Haven, Connecticut, USA.
Kai ChenYale Center On Climate Change and Health, Yale School of Public Health, New Haven, Connecticut, USA.
Michelle C OddenDepartment of Epidemiology and Population Health, Stanford University, Stanford, California, USA.

Funding

Exceptional Survival: Trajectories to Functional Aging (CHS All Stars)R01AG023629 · NIA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI NEWMAN, ANNE B. · 2004 to 2016
$9.5M
CARDIOVASCULAR HEALTH STUDY (CHS) - TASK AREA C, STUDY CLOSEOUT75N92021D00006 · NHLBI · UNIVERSITY OF WASHINGTON · PI PSATY, BRUCE · 2021 to 2024
$8.4M
CHS research resources for the cardiovascular health of older adultsU01HL130114 · NHLBI · UNIVERSITY OF WASHINGTON · PI BURKE, GREGORY L, KRONMAL, RICHARD A · 2016 to 2019
$6.6M
CHS Events Follow-up StudyU01HL080295 · NHLBI · UNIVERSITY OF WASHINGTON · PI PSATY, BRUCE M · 2005 to 2008
$4.6M
Study of Cardiac Mechanics in Systemic HypertensionR01HL107577 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SHAH, SANJIV J · 2011 to 2019
$4.1M
Infrastructure for mentored access to CHS data and specimensR01HL172803 · NHLBI · UNIVERSITY OF WASHINGTON · PI James S Floyd, Michelle Christina Odden · 2025 to 2026
$2.7M
CHS-Transition PhaseN01HC55222 · NHLBI · PI , · 2007 to 2007
$575k
CENTRAL BLOOD ANALYSIS LABORATORY FOR CHSN01HC085086 · HC · UNIVERSITY OF VERMONT &ST AGRIC COLLEGE · PI TRACY, RUSSELL P · 1988 to 2000
–
CORONARY HEART DISEASE &STROKE IN PEOPLE AGED 65 TO 84N01HC085079 · HC · UNIVERSITY OF WASHINGTON · 1988 to 2005
–
CORONARY HEART DISEASE &STROKE IN THE ELDERLYN01HC085080 · HC · WAKE FOREST UNIVERSITY · PI BURKE, GREGORY L · 1988 to 2000
–
CHS-Transition Phase -268055222-268055222N01HC055222 · HC · UNIVERSITY OF WASHINGTON · PI KRONMAL, RICHARD A · 2005 to 2006
–
CORONARY HEART DISEASE &STROKE IN PEOPLE AGED 65-84N01HC085081 · HC · JOHNS HOPKINS UNIVERSITY · PI FRIED, LINDA P · 1988 to 2000
–
National Heart, Lung, and Blood Institute (NHLBI) HL172803National Heart, Lung, and Blood Institute (NHLBI) U01HL080295National Heart, Lung, and Blood Institute (NHLBI) U01HL130114National Institute of Neurological Disorders and Stroke (NINDS) R01AG023629National Institute on Aging (NIA) R01HL107577NHLBI NIH HHS 75N92021D00006NHLBI NIH HHS HHSN268200800007CNHLBI NIH HHS HHSN268201200036CNHLBI NIH HHS HHSN268201800001CNHLBI NIH HHS N01 HC055222NHLBI NIH HHS N01 HC085079NHLBI NIH HHS N01 HC085080NHLBI NIH HHS N01 HC085081NHLBI NIH HHS N01 HC085082NHLBI NIH HHS N01 HC085083NHLBI NIH HHS N01 HC085086NHLBI NIH HHS N01HC55222NHLBI NIH HHS N01HC85079NHLBI NIH HHS N01HC85080NHLBI NIH HHS N01HC85081NHLBI NIH HHS N01HC85082NHLBI NIH HHS N01HC85083NHLBI NIH HHS N01HC85086NHLBI NIH HHS R01 HL107577NHLBI NIH HHS R01 HL172803NHLBI NIH HHS U01 HL080295NHLBI NIH HHS U01 HL130114NIA NIH HHS R01 AG023629
6 · The paper itself

Abstract

purposeGround-level ozone (O

methodsWe applied speckle-tracking echocardiography (STE) to explore the relationship between chronic residential gaseous air pollution exposure and cardiac mechanics in community-dwelling older adults largely free of baseline heart disease. Average annual address-specific concentrations of O

resultsOne thousand five hundred and seventy-six individuals were included in the analysis. We found that each part per billion increase in O

conclusionsOzone exposure may be associated with subclinical markers of diastolic dysfunction, while NO

Indexed as

Air PollutantsCardiovascular DiseasesEchocardiographyHeart VentriclesNitrogen DioxideOzoneAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedAir PollutantsNitrogen DioxideOzoneair pollutioncardiac mechanicsdiastolic dysfunctionechocardiographyenvironmental healthepidemiologymyocardial strainspeckle‐tracking echocardiography

Identifiers

PMID41146536
PMCPMC12664112

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.