ArticleThe European journal of neuroscience2025
Synaptic Plasticity of D1 and D2 Types of Neurons in the Central Amygdala After Sucrose and Cocaine Exposure.
Article in The European journal of neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- DRD1 and DRD2 dopamine-sensitive neurons in the central amygdala respond differently to rewarding and aversive stimuli.Translational psychiatry · 2026Article
- Synaptic Plasticity of D1 and D2 Types of Neurons in the Central Amygdala After Sucrose and Cocaine Exposure.The European journal of neuroscience · 2025Article
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3 authors.
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Abstract
Dopamine-sensitive neurons are organized in two classes of cells, expressing D1- or D2-type dopamine receptors, and often mediate opposing aspects of reward-oriented behaviors. Here, we focused on D1- and D2-type neurons in the central amygdala, a brain structure critically involved in processing emotion-related stimuli. We demonstrated the distinct composition of the central amygdala based on these receptors: the lateral part (CeL) consists almost exclusively of D2-type neurons, while the medial part (CeM) contains a mix of both D1- and D2-type neurons. Recording excitatory postsynaptic currents' frequency in D1 and D2-type neurons after exposing mice to rewarding stimuli, we showed that in the CeM, cocaine injections trigger opposite changes of spontaneous excitatory synaptic transmission than exposure to sucrose.
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