Evidence map›Paper›PMID 41146433›Full record

ReviewChinese medical journal2026

Cannabinoids in immune system-related diseases: From bench to clinic.

Wenyu Zhang, Buzhuo Chen, Yanting Cao, Wangrui Lei, Huadong Zhao, Yang Yang, Jiayou Tang

Abstract readReview
In one paragraph

Review in Chinese medical journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wenyu ZhangXi'an Key Laboratory of Innovative Drug Research for Heart Failure, School of Medicine, Faculty of Life Sciences and Medicine, Northwest University, Xi'an, Shannxi 710069, China.
Buzhuo ChenSchool of Medicine, Shanghai Jiao Tong University, Shanghai 200025, China.
Yanting CaoXi'an Key Laboratory of Innovative Drug Research for Heart Failure, School of Medicine, Faculty of Life Sciences and Medicine, Northwest University, Xi'an, Shannxi 710069, China.
Wangrui LeiXi'an Key Laboratory of Innovative Drug Research for Heart Failure, School of Medicine, Faculty of Life Sciences and Medicine, Northwest University, Xi'an, Shannxi 710069, China.
Huadong ZhaoDepartment of General Surgery, Tangdu Hospital, The Airforce Medical University, Xi'an, Shaanxi 710038, China.
Yang YangXi'an Key Laboratory of Innovative Drug Research for Heart Failure, School of Medicine, Faculty of Life Sciences and Medicine, Northwest University, Xi'an, Shannxi 710069, China.
Jiayou TangDepartment of Cardiovascular Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, Shaanxi 710032, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

abstractAs a psychoactive drug, marijuana is used for recreational purposes. Given its addictive nature and the serious damage it causes to both individual health and social stability, marijuana has been banned in most countries worldwide. In recent years, with the continuous improvement of basic research, researchers have discovered the role of cannabinoids, the primary active ingredient in marijuana, in multiple human systems. Research found that cannabinoids can regulate immune system function and have therapeutic potential in immune system-related diseases. However, the use of cannabinoids still poses certain hazards. For instance, cannabinoids can exert certain impacts on fetal nervous system development; cannabinoids use can lead to adverse reactions such as dizziness, nausea, and dry mouth. Moreover, there are still numerous contradictions in current research on the effects of cannabinoids, and the mechanisms by which cannabinoids exert protective effects in certain diseases remain unelucidated. In this review, we systematically discuss the endocannabinoid system and summarize the molecular and cellular bases of cannabinoid function in the immune system, and elucidate the effects of cannabinoids on immune system-related diseases.

Indexed as

CannabinoidsImmune SystemImmune System DiseasesAnimalsEndocannabinoidsHumansCannabinoidsEndocannabinoidsAgentsCannabinoidCannabinoid receptorEndocannabinoid systemImmune system

Identifiers

PMID41146433
PMCPMC13186158

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.