Evidence map›Paper›PMID 41146390›Full record

ArticleKorean journal of radiology2025

Feasibility of Viscosity Imaging and Shear Wave Elastography for Diagnosing Diabetic Peripheral Neuropathy.

Shuangxiu Tan, Siwen Zhao, Zhibin Jin, Jing Yao, Weimin Wang, Chenxi Li, Weijing Zhang

Abstract read
In one paragraph

Article in Korean journal of radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Shuangxiu TanDepartment of Ultrasound Medicine, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.ORCID https://orcid.org/0009-0007-1355-1767
Siwen ZhaoDepartment of Endocrinology, Nanjing Drum Tower Hospital Clinical College of Jiangsu University, Nanjing, China.ORCID https://orcid.org/0009-0003-1328-6597
Zhibin JinDepartment of Ultrasound Medicine, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.ORCID https://orcid.org/0000-0003-4883-8868
Jing YaoDepartment of Ultrasound Medicine, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.ORCID https://orcid.org/0000-0002-8867-3079
Weimin WangDepartment of Endocrinology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Branch of National Clinical Research Centre for Metabolic Diseases, Nanjing, China.ORCID https://orcid.org/0000-0001-6931-8509
Chenxi LiDepartment of Endocrinology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Branch of National Clinical Research Centre for Metabolic Diseases, Nanjing, China. lichenxi@smail.nju.edu.cn.ORCID https://orcid.org/0000-0001-7489-7234
Weijing ZhangDepartment of Ultrasound Medicine, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China. weijing_zhang@163.com.ORCID https://orcid.org/0009-0004-7948-9247

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the diagnostic potential of viscosity (Vi) imaging and shear wave elastography (SWE) of the tibial nerve in diabetic peripheral neuropathy (DPN). MATERIALS AND

methodsThis prospective study enrolled 40 patients with type II diabetes mellitus (T2DM) accompanied by DPN, 40 T2DM patients without DPN, and 40 healthy controls between January 2025 and April 2025. The bilateral tibial nerves were examined using SWE and Vi imaging to measure shear wave speed (Cs, m/s) and Vi (Pa·s). The reference standards for the DPN diagnosis comprised clinical examination, electromyography, and quantitative sensory testing. Diagnostic performance was assessed using receiver operating characteristic curve analysis and by calculating sensitivity and specificity at the optimal cutoff values for Cs and Vi. The areas under the curve (AUCs) were compared using DeLong's test.

resultsOn the right side, the DPN group exhibited significantly higher Cs

conclusionVi imaging quantifies nerve Vi in DPN and offers a novel, non-invasive diagnostic approach to distinguish patients with DPN from those without the condition. However, viscoelastic imaging does not provide greater diagnostic value than SWE.

Indexed as

Diabetic NeuropathiesElasticity Imaging TechniquesTibial NerveAdultAgedDiabetes Mellitus, Type 2Feasibility StudiesFemaleHumansMaleMiddle AgedProspective StudiesSensitivity and SpecificityViscosityDiabetic peripheral neuropathyDiagnostic valueShear wave elastographyUltrasonographyViscosity

Identifiers

PMID41146390
PMCPMC12568767

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.