Evidence map›Paper›PMID 41146382›Full record

ArticleBMJ open2025

Adaptation of the serious illness conversation guide to a multicultural context in Singapore: a qualitative study.

Chandrika Ramakrishnan, Anna So Youn Lee, Chetna Malhotra, Gillian Li Gek Phua, Alethea Yee, Shirlyn Hui-Shan Neo

Registry-linked trialAbstract read
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07733973 (Evaluating the Effectiveness, Acceptability and Feasibility of a Communication and Care Coordinator), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07733973 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Evaluating the Effectiveness, Acceptability and Feasibility of a Communication and Care Coordinator (CCC) Model in Facilitating Serious Illness Communication (SIC) and Care in Patients With Cancer

TypeinterventionalSponsorNational Cancer Centre, SingaporeRan2026 to 2029Enrolled560ConditionsCancerArmsCCC Intervention
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chandrika RamakrishnanLien Centre for Palliative Care, Duke-NUS Medical School, Singapore.ORCID http://orcid.org/0009-0002-4623-0357
Anna So Youn LeeLien Centre for Palliative Care, Duke-NUS Medical School, Singapore.
Chetna MalhotraLien Centre for Palliative Care, Duke-NUS Medical School, Singapore.ORCID http://orcid.org/0000-0002-5380-0525
Gillian Li Gek PhuaLien Centre for Palliative Care, Duke-NUS Medical School, Singapore.ORCID http://orcid.org/0000-0002-2034-9723
Alethea YeeLien Centre for Palliative Care, Duke-NUS Medical School, Singapore.
Shirlyn Hui-Shan NeoLien Centre for Palliative Care, Duke-NUS Medical School, Singapore shirlyn.neo.h.s@singhealth.com.sg.ORCID http://orcid.org/0000-0003-2811-1661

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo adapt the Serious Illness Conversation Guide (SICG), Ariadne Labs, Massachusetts USA, to a local Singapore version and evaluate its acceptability.

designQualitative study using semistructured interviews.

participants49 participants (30 patients with serious illnesses, five family caregivers and 14 healthcare providers (HCP)) recruited from three public hospitals in Singapore.

settingFace-to-face or virtual indepth interviews.

methodsGuided by the Heuristic Framework and Cultural Sensitivity model, we employed a multi-stage iterative design. Starting with the original SICG, we iterated the guide following three rounds of cognitive interviews among patients followed by expert consultation (n=4) to derive a local version, subsequently reviewed by caregivers and HCP. We assessed acceptability of the SICG using traffic light colour codes-red (unacceptable), orange (needs change) and green (no change) and gathered suggestions to rephrase them. Using content analysis, we compared acceptability of questions as proportion of red, orange and green responses at each interview round and inductively derived themes reflecting views towards the guide.

resultsThe original SICG showed low acceptability, and most questions received high proportions of red responses. Negative words and phrases dampening hope, lack of comprehension due to complex framing and cultural insensitivity to prognostic discussions were key themes reflecting low acceptability. Surface and deep structural revisions that centred around positive framing with hopeful language, focusing on current values and individualising conversations ('use if appropriate' prompts) significantly improved the guide's acceptability.

conclusionWe derived a local Singapore SICG that aligns with the core elements of the original guide and fosters cultural sensitivity. The adapted version could be further tested in other Asian countries.

Indexed as

CommunicationCritical IllnessAdultAgedCaregiversCultural DiversityFemaleHealth PersonnelHumansInterviews as TopicMaleMiddle AgedQualitative ResearchSingaporePALLIATIVE CAREPatient-Centered CareQUALITATIVE RESEARCH

Identifiers

PMID41146382
PMCPMC12557724

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.