Evidence map›Paper›PMID 41146351›Full record

ArticleAnimal microbiome2025

Modulatory effects of Boletus edulis on the gut microbiota in Atlantic salmon (Salmo salar) utilizing an artificial teleost gut model.

Alexandru S Barcan, Joseph L Humble, Rares A Barcan, Eve Hughes, Brendan Robertson, Douglas J Morrison, Emanuel Vamanu, Philip McGinnity, Martin S Llewellyn

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Animal microbiome, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alexandru S BarcanSBOHVM, University of Glasgow, Graham Kerr Building, Glasgow, G12 8QQ, UK.
Joseph L HumbleSBOHVM, University of Glasgow, Graham Kerr Building, Glasgow, G12 8QQ, UK.
Rares A BarcanMaths & Physical Sciences, University of Sussex, Falmer, Brighton, BN1 9RH, UK.
Eve HughesSBOHVM, University of Glasgow, Graham Kerr Building, Glasgow, G12 8QQ, UK.
Brendan RobertsonSBOHVM, University of Glasgow, Graham Kerr Building, Glasgow, G12 8QQ, UK.
Douglas J MorrisonScottish Universities Environmental Research Centre (SUERC), College of Science and Engineering, University of Glasgow, Glasgow, UK.
Emanuel VamanuFaculty of Biotechnology, University of Agricultural Sciences and Veterinary Medicine, 011464, Bucharest, Romania.
Philip McGinnitySchool of Biological, Earth & Environmental Sciences, University College Cork, Cork, Ireland.
Martin S LlewellynSBOHVM, University of Glasgow, Graham Kerr Building, Glasgow, G12 8QQ, UK. martin.llewellyn@glasgow.ac.uk.

Funding

Agency for Student Loans and Scholarships (https://roburse.ro) H.G. no. 118/2023BBSRC-SFI BB/P001203/1.
6 · The paper itself

Abstract

backgroundIn aquaculture, several functional mushrooms have been efficiently used as prebiotics, impacting gut microbiota, increasing growth, and delivering antioxidant advantages to a variety of finfish species. However, the potential of Boletus edulis, the 'porcini' or 'penny bun' to influence the gut microbiota of Salmo salar has yet to be studied. Here, we investigated the prebiotic effect of Boletus edulis extract (BEE) on the gut microbiota of farmed Atlantic salmon via an in vitro gut model (SalmoSim).

resultsNotable changes in the production of short-chain fatty acids and microbial diversity were observed upon the addition of BEE. In particular, increased fiber fermentation was suggested by the decreasing concentrations of ammonia and increasing levels of acetate and propionate. Moreover, the 10% BEE improved the absorption of amino acids and increased the digestibility of crude protein, promoting a more diverse microbial community and reducing the accumulation of nitrogenous waste.

conclusionsThe results of the present study revealed that the addition of BEE efficiently altered the gut microbiota, increasing microbial diversity, supporting beneficial short-chain fatty acid synthesis, and improving nutritional absorption in Atlantic salmon.

Indexed as

AquacultureAtlantic salmonBoletus edulisGut microbiotaMushroomsNutrient absorptionPrebiotics

Identifiers

PMID41146351
PMCPMC12560320

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.