Trial reportEuropean journal of medical research2025
Clinical outcome of Nd:YAG laser and bioactive glass combined use for dentin hypersensitivity after scaling and root planning: a short-term comparative study.
Trial report in European journal of medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Role of lasers in restorative dentistry: a review and update.Frontiers in dental medicine · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
aimThis randomized controlled trial aimed to assess the efficacy of a combined Nd:YAG laser and bioactive glass (BAG) for dentin hypersensitivity following scaling and root planning (SRP). The study compared various desensitization protocols and evaluated the time-dependent effects of immediate desensitization therapy post-SRP.
methods80 patients with chronic periodontitis (200 sensitive teeth) were randomly assigned to five groups: group A (BAG), group B (Nd:YAG laser), group C (Nd:YAG laser + BAG), group D (BAG + Nd:YAG laser), and group E (control). Hypersensitivity was assessed via air-blast stimulation and measured on a Visual Analogue Scale (VAS) at baseline (T0), immediately after intervention (T1), and at 1-, 4-, and 8-week (T2-T4) post-treatment. Between-group comparisons of baseline characteristics and post-treatment measurements were analyzed with one-way ANOVA. Longitudinal comparisons across timepoints were evaluated using repeated-measures ANOVA. Categorical variables were compared by chi-square test.
resultsNo significant differences in demographic characteristics or baseline VAS scores were observed across the groups before treatment (P > 0.05). All interventional groups (A-D) showed significant and sustained reductions in VAS scores relative to both baseline and control (all P < 0.001), with group D achieving the greatest improvement at T4 (2.00 ± 0.68, P < 0.05 vs. group C). Effectiveness rates were also significantly higher in groups A-D than in group E (all P < 0.001). Combination therapies (C and D) proved superior to monotherapies (A and B), with group D maintaining the highest effectiveness rate through T4 (92.5%). A gradual decline in effectiveness was observed over time, being least pronounced in group D.
conclusionsThe combined application of BAG and Nd:YAG laser therapy demonstrated a significant reduction in dentin hypersensitivity post-SRP, exhibiting superior and sustained efficacy compared to monotherapies. Furthermore, the sequential treatment involving BAG applied prior to Nd:YAG laser irradiation showed the most pronounced therapeutic effect in symptom alleviation.
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