Evidence map›Paper›PMID 41146284›Full record

ArticleImplementation science communications2025

"Though there are some challenges, we try our best to follow the guidelines": a qualitative study exploring determinants of providing guideline-adherent care to hospitalized children in Kenya.

Megan M Coe, Riffat Ara Shawon, Mary Masheti, Chrisantus Oduol, Phlona Amam, Geofrey Okoth Olieng'o, Molline Timbwa, Martin Kamui, Johnstone Thitiri, Sarah Gimbel and 2 more

Abstract read
In one paragraph

Article in Implementation science communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Megan M CoeDepartment of Child, Family, and Population Health Nursing, University of Washington, Seattle, WA, USA. megan.coe@stjude.org.ORCID http://orcid.org/0000-0001-9317-4138
Riffat Ara ShawonDepartment of Global Health, University of Washington, Seattle, WA, USA.
Mary MashetiKenya Medical Research Institute, Nairobi, Kenya.
Chrisantus OduolKenya Medical Research Institute, Nairobi, Kenya.
Phlona AmamKenya Medical Research Institute, Nairobi, Kenya.
Geofrey Okoth Olieng'oKenya Medical Research Institute, Nairobi, Kenya.
Molline TimbwaKEMRI-Wellcome Trust, Nairobi, Kenya.
Martin KamuiKEMRI-Wellcome Trust, Nairobi, Kenya.
Johnstone ThitiriKEMRI-Wellcome Trust, Nairobi, Kenya.
Sarah GimbelDepartment of Child, Family, and Population Health Nursing, University of Washington, Seattle, WA, USA.
Benson Singa *Kenya Medical Research Institute, Nairobi, Kenya.
Arianna Rubin Means *Department of Global Health, University of Washington, Seattle, WA, USA.

Funding

RiNGH (Research in Nursing & Global Health) Training ProgramT32NR019761 · NINR · UNIVERSITY OF WASHINGTON · PI KOHLER, PAMELA, PINTYE, JILLIAN · 2021 to 2025
$1.4M
Prevalence and correlates of pediatric guideline deviation across 9 health facilitiesR03HD099270 · NICHD · UNIVERSITY OF WASHINGTON · PI MEANS, ARIANNA RUBIN · 2019 to 2020
$156k
National Institute of Child Health and Human Development R03HD099270NICHD NIH HHS R03 HD099270NINR NIH HHS T32 NR019761
6 · The paper itself

Abstract

backgroundClinical treatment guidelines are designed to improve quality of care by offering clear recommendations for health workers; however, across many settings, implementing guidelines is a challenge. For over 20 years, comprehensive World Health Organization guidelines for care of hospitalized children have provided guidance for treating the primary causes of childhood death. These recommendations were adapted in Kenya and codified in the Basic Paediatric Protocol; however, adherence to these evidence-based interventions remains suboptimal.

methodsThis qualitative study identified the barriers and facilitators of providing guideline-adherent care to children admitted to two hospitals in Kenya. The semi-structured question guide was informed by the Theoretical Domains Framework (TDF). Three focus group discussions and 16 in-depth interviews were conducted with 35 health workers. Participants were nurses, doctors, clinical officers, or nutritionists (including in-charges and clinical supervisors). Interviews were audio recorded and transcribed. Transcripts were coded using a TDF-based codebook, validated, and analyzed for themes.

resultsTDF domains with the greatest influence on the thematic findings were environmental context and resources, social influences, beliefs about consequences, and beliefs about capabilities. Health workers were knowledgeable about guidelines and felt strongly that adherence to them was beneficial; however, they also faced barriers implementing them. Challenges related to the environmental context were pervasive, including shortages of staff and supplies. Participants praised the simplicity of guidelines but also noted that simplified diagnostic criteria don't align with complex patient presentations. While guidelines empowered some nurses to make clinical decisions, respondents reported that strict professional roles sometimes delayed diagnosis and treatment. Further, health workers reported some deviations were intentional (ex. when guidelines were not aligned to their beliefs) and other times they were unintentional (ex. when complex patient presentations make guideline adherence difficult).

conclusionsKnowledge of guidelines and motivation to use them were not major determinants in this analysis. Rather, human and material resource shortages presented the greatest barrier to guideline adherence in this setting. Improving guidelines by involving health workers in participatory development of guidelines would improve both clarity and feasibility. Health workers are well-versed in guideline recommendations, so educational strategies should focus on knowledge gaps or changes in the latest version of guidelines.

Indexed as

GuidelineHospitalKenyaPediatricQualitativeTheoretical Domains Framework

Identifiers

PMID41146284
PMCPMC12560299

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.