Evidence map›Paper›PMID 41146275›Full record

ArticleAddiction science & clinical practice2025

Adaptations and modifications to the 15-method in Danish general practice classified using the framework for reporting adaptations and modifications to evidence-based interventions (FRAME).

Peter Næsborg Schøler, Per Nilsen, Sanne Rasmussen, Jens Søndergaard, Anette Søgaard Nielsen

Abstract read
In one paragraph

Article in Addiction science & clinical practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Peter Næsborg SchølerDepartment of Clinical Research, Unit for Clinical Alcohol Research, Research Unit of Psychiatry, University of Southern Denmark, J.B. Winsløwsvej 18, ent. 220B, First Floor, Odense C, DK-5000, Denmark. pscholer@health.sdu.dk.
Per NilsenDepartment of Health, Medicine and Caring Sciences, Linköping University, Linköping, Sweden.
Sanne RasmussenDepartment of Public Health, Research Unit of General Practice, University of Southern Denmark, Odense, Denmark.
Jens SøndergaardDepartment of Public Health, Research Unit of General Practice, University of Southern Denmark, Odense, Denmark.
Anette Søgaard NielsenDepartment of Clinical Research, Unit for Clinical Alcohol Research, Research Unit of Psychiatry, University of Southern Denmark, J.B. Winsløwsvej 18, ent. 220B, First Floor, Odense C, DK-5000, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUnhealthy alcohol use is a major global public health problem, yet alcohol problems often remain unaddressed in primary care. The 15-method, developed in Sweden, offers a flexible, patient-centered approach to alcohol-related issues using opportunistic screening and stepped-care treatment in the same setting. The present study describes adaptations and modifications made to the 15-method by Danish healthcare professionals during a randomized controlled trial testing the 15-method’s effectiveness in Danish general practice.

methodsData for the present qualitative study were individual and group interviews with 28 healthcare professionals from 12 Danish general practices enrolled in the Identification and Treatment of Alcohol Problems in Primary Care (iTAPP) study, a stepped-wedge cluster randomized controlled trial. Interviews focused on innovation and implementation process determinants from the Consolidated Framework for Implementation Science (CFIR). By means of the Framework for Reporting Adaptations and Modifications to Evidence-based interventions (FRAME), data were analyzed to identify modifications to the 15-method when implemented in daily use.

resultsFour distinct modifications were identified: a loosening of the method’s structure, condensed use of the method’s materials, modification of screening procedures, and integration into existing clinical procedures. Half of the changes were unplanned, and half were fidelity-consistent. Three of four changes occurred on practice level and were made by general practitioners. The most common goal of the changes was to increase patient reach and engagement. More training and structured follow-up were also identified as important to increase healthcare professionals’ confidence in delivering the 15-method.

conclusionGeneral practitioners and nurses generally find the 15-method suitable for their work in Danish general practice, and the method can be readily implemented with minor adaptations. More training and implementation planning may promote higher utilization and more consistent use, ultimately increasing the method’s sustainability and effectiveness.

Indexed as

AlcoholismEvidence-Based PracticeGeneral PracticeDenmarkFemaleHumansMalePrimary Health CareQualitative ResearchAlcohol interventionFramework for reporting adaptations and modifications to evidence-based interventionsImplementation sciencePrimary careScreening and brief intervention

Identifiers

PMID41146275
PMCPMC12557837

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.