Evidence map›Paper›PMID 41146115›Full record

ArticleBMC medical education2025

Generative AI in medical education: feasibility and educational value of LLM-generated clinical cases with MCQs.

Qi Zhang, Zijing Huang, Yuqiang Huang, Geng Wang, Riping Zhang, Jianling Yang, Yinglin Cheng, Binyao Chen, Hongxi Wang, Kunliang Qiu and 1 more

Abstract read
In one paragraph

Article in BMC medical education, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Qi ZhangJoint Shantou International Eye Center of Shantou University and The Chinese University of Hong Kong, North Dongxia Road, Shantou, 515041, Guangdong, China.ORCID http://orcid.org/0000-0002-1914-9695
Zijing HuangJoint Shantou International Eye Center of Shantou University and The Chinese University of Hong Kong, North Dongxia Road, Shantou, 515041, Guangdong, China.
Yuqiang HuangJoint Shantou International Eye Center of Shantou University and The Chinese University of Hong Kong, North Dongxia Road, Shantou, 515041, Guangdong, China.
Geng WangJoint Shantou International Eye Center of Shantou University and The Chinese University of Hong Kong, North Dongxia Road, Shantou, 515041, Guangdong, China.
Riping ZhangJoint Shantou International Eye Center of Shantou University and The Chinese University of Hong Kong, North Dongxia Road, Shantou, 515041, Guangdong, China.
Jianling YangJoint Shantou International Eye Center of Shantou University and The Chinese University of Hong Kong, North Dongxia Road, Shantou, 515041, Guangdong, China.
Yinglin ChengJoint Shantou International Eye Center of Shantou University and The Chinese University of Hong Kong, North Dongxia Road, Shantou, 515041, Guangdong, China.
Binyao ChenJoint Shantou International Eye Center of Shantou University and The Chinese University of Hong Kong, North Dongxia Road, Shantou, 515041, Guangdong, China.
Hongxi WangJoint Shantou International Eye Center of Shantou University and The Chinese University of Hong Kong, North Dongxia Road, Shantou, 515041, Guangdong, China.
Kunliang QiuJoint Shantou International Eye Center of Shantou University and The Chinese University of Hong Kong, North Dongxia Road, Shantou, 515041, Guangdong, China.
Haoyu ChenJoint Shantou International Eye Center of Shantou University and The Chinese University of Hong Kong, North Dongxia Road, Shantou, 515041, Guangdong, China. drchenhaoyu@gmail.com.ORCID http://orcid.org/0000-0003-0676-4610

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the feasibility and educational value of employing large language models (LLMs) to generate clinical case scenario with multiple-choice questions (MCQs) for undergraduate medical education.

methodsTwelve ophthalmology clinical case scenarios with MCQs generated by ChatGPT 4.0 were assessed for quality by eight teachers. High-scoring cases with MCQs were selected for review classes to test students' learning. Student perceptions were collected via in-class and after-class questionnaires using a 5-point Likert scale.

resultsThe average quality score of the 12 cases with MCQs was 52.33 ± 5.44 (range: 48-54.25; max = 60). There were statistical differences in the teachers' scores for identical clinical cases (F = 16.050, P < 0.001). Among 20 students, 95% agreed AI-generated cases enriched learning resources, 80% reported improved interdisciplinary integration and learning efficiency, while 85% used LLMs for post-class practice but raised concerns about content accuracy and difficulty calibration.

conclusionLLMs like ChatGPT can rapidly generate clinically relevant case scenarios and MCQs under precise prompts, offering a novel tool for educators and learners. However, expert review remains critical to mitigate risks of AI hallucinations (observed in 16.67% of cases, 2/12) and ensure alignment with curricular standards. Key issues included contradictions in imaging descriptions (e.g., inappropriate use of high-frequency ultrasound for chalazion) and diagnostic logic (e.g., inconsistent gonioscopy findings), underscoring the necessity of human oversight to refine content accuracy and educational utility.

Indexed as

Artificial IntelligenceEducational MeasurementEducation, Medical, UndergraduateOphthalmologyFeasibility StudiesHumansStudents, MedicalSurveys and QuestionnairesClinical case scenariosLarge language modelsMultiple-choice questionsUndergraduate medical education

Identifiers

PMID41146115
PMCPMC12560302

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.