Evidence map›Paper›PMID 41146097›Full record

ArticleBMC nephrology2025

Hospital-based health technology assessment of central dialysis fluid delivery system for hemodialysis patients.

Wendi Cheng, Haiyin Wang, Jiangzi Yuan, Ying Li, Yashuang Luo, Yuyan Fu, Leyi Gu, Jun Xue, Chunlin Jin, Yin Zheng

Abstract read
In one paragraph

Article in BMC nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Wendi ChengShanghai Health Development Research Center, (Shanghai Medical Information Center), Shanghai, China.ORCID 0000-0002-4198-7767
Haiyin WangShanghai Health Development Research Center, (Shanghai Medical Information Center), Shanghai, China.
Jiangzi YuanDepartment of Nephrology, Baoshan Branch of Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Ying LiDepartment of Nephrology, Shanghai Jiading District Central Hospital, Shanghai, China.
Yashuang LuoShanghai Health Development Research Center, (Shanghai Medical Information Center), Shanghai, China.
Yuyan FuShanghai Health Development Research Center, (Shanghai Medical Information Center), Shanghai, China.
Leyi GuDepartment of Nephrolgoy, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Jun XueDepartment of Nephrology, Huashan Hospital, Fudan University, Shanghai, China.
Chunlin JinShanghai Health Development Research Center, (Shanghai Medical Information Center), Shanghai, China. jinchunlin@shdrc.org.
Yin ZhengDepartment of Nephrology, Huashan Hospital, Fudan University, Shanghai, China. zhengyin@huashan.org.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study employed a hospital-based health technology assessment (HB-HTA) to evaluate the economic value of the central dialysis fluid delivery system (CDDS) compared to the single-patient dialysis fluid delivery system (SPDDS) in hemodialysis. The findings offer evidence to support hospital procurement and clinical implementation decisions regarding CDDS.

methodsA comparative cost analysis was conducted using micro-costing data collected from three hospitals. Costs were estimated for both CDDS and SPDDS, and economic efficiency was evaluated across multiple hemodialysis machine configuration scales. The analysis included total costs, cost structures, and cost savings, along with their constituent components, to identify scenarios in which CDDS provides economic advantages.

resultsIn a dialysis center with 6 hemodialysis machines operating two shifts per day and serving 12 patients daily, CDDS reduced costs by 0.05% compared to SPDDS. As the number of machines increased from 6 to 50, the cost reduction rate rose from 0.05% to 21.08%, demonstrating enhanced economic benefits at larger scales. In a 50-machine center, CDDS saved approximately RMB 84 per treatment session and RMB 2,601,108 annually. The majority of cost savings came from reductions in consumables (74%) and labor (24%). One-way sensitivity analysis confirmed that CDDS consistently yielded cost savings, supporting the robustness of the costing model.

conclusionCDDS demonstrates significant economic value over SPDDS by reducing consumable and labor costs, proving to be a cost-effective solution in dialysis centers with 6 or more machines serving at least 12 patients daily. Clinical engineers play a key role in its implementation. CDDS is suitable for promotion in medium- to large-scale dialysis centers in China.

Indexed as

Renal DialysisTechnology Assessment, BiomedicalCost-Benefit AnalysisCost SavingsHumansCentral dialysis fluid delivery system (CDDS)Economic valueHemodialysisHospital-based health technology assessment (HB-HTA)Micro-costingSingle-patient dialysis fluid delivery system (SPDDS)

Identifiers

PMID41146097
PMCPMC12560572

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.