Evidence map›Paper›PMID 41146068›Full record

Trial reportBMC pregnancy and childbirth2025

Early psycho-social support of pregnant women at risk for preeclampsia and fetal intrauterine growth restriction.

Franziska Epple, Jörg Reichert, Mario Rüdiger, Cahit Birdir, Lars Mense

Registry-linked trialAbstract readClinical TrialMulticenter Study
In one paragraph

Trial report in BMC pregnancy and childbirth, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04514276 (Inter- and Multidisciplinary, Cross-sectoral Feto-neonatal Pathway for High-risk Pregnant Women Because of Fetal Growth Restriction), which is not on this map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04514276 naunknown statusnot on this map

Inter- and Multidisciplinary, Cross-sectoral Feto-neonatal Pathway for High-risk Pregnant Women Because of Fetal Growth Restriction

TypeinterventionalSponsorTechnische Universität DresdenRan2020 to 2024Enrolled828ConditionsPre-Eclampsia, Intrauterine Growth Restriction, Maternal Care for Known or Suspected Poor Fetal GrowthArmsconsecutive fetoneonatal healthcare pathway
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Franziska EppleDepartment of Pediatrics, Division of Neonatology & Pediatric Intensive Care Medicine, University Hospital Carl Gustav Carus Dresden, TU Dresden, German Center for Child and Adolescent Health (DZKJ), Partner Site Leipzig/Dresden, Fetscherstrasse 74, 01307, Dresden, Germany.
Jörg ReichertDepartment of Pediatrics, Division of Neonatology & Pediatric Intensive Care Medicine, University Hospital Carl Gustav Carus Dresden, TU Dresden, German Center for Child and Adolescent Health (DZKJ), Partner Site Leipzig/Dresden, Fetscherstrasse 74, 01307, Dresden, Germany.
Mario RüdigerDepartment of Pediatrics, Division of Neonatology & Pediatric Intensive Care Medicine, University Hospital Carl Gustav Carus Dresden, TU Dresden, German Center for Child and Adolescent Health (DZKJ), Partner Site Leipzig/Dresden, Fetscherstrasse 74, 01307, Dresden, Germany.
Cahit BirdirDepartment of Gynecology, Division of Obstetrics, University Hospital Carl Gustav Carus Dresden, TU Dresden, Fetscherstrasse 74, 01307, Dresden, Germany.
Lars MenseDepartment of Pediatrics, Division of Neonatology & Pediatric Intensive Care Medicine, University Hospital Carl Gustav Carus Dresden, TU Dresden, German Center for Child and Adolescent Health (DZKJ), Partner Site Leipzig/Dresden, Fetscherstrasse 74, 01307, Dresden, Germany. Lars.Mense@ukdd.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe risk of preeclampsia and intrauterine growth restriction can be assessed in the first trimester combining maternal characteristics, biophysical and biochemical measurements. The early risk identification allows targeted follow up and prophylactic treatment with acetylsalicylic acid but potentially influences the pregnant woman's experience and mental well-being. A structured follow-up involving psycho-social support might improve patient care and decrease the burden of being identified as a woman at risk of a potentially life-threatening pregnancy complication. We describe the utilization of an early psycho-social intervention and concerns raised by the participants.

methodsSecondary analysis of the early psycho-social interventions as part of a prospective cohort study.

results92.1% (441/479) participated in the early psycho-social intervention. 86.6% had at least one risk and load factor: 56.7% reported fears, 44.0% had mental illnesses in past or present and 36.7% reported social constraints. Experiences of violence were reported by 25.9%. Additional support was required in 27.7% of cases. More than 90% of women recommended a similar conversation for other women in a similar situation.

conclusionsAn early psycho-social intervention for pregnant women at risk is well accepted and many report risk and load factors which can be addressed by the psychologist. Some women require additional support which can be instituted afterwards.

trial registrationThe study was registered at clinicaltrials.gov (number NCT04514276, registered 14/08/2020) and DRKS (number DRKS00017713, registered 09/06/2020).

Indexed as

Fetal Growth RetardationPre-EclampsiaPregnant PeoplePrenatal CareSocial SupportAdultFemaleHumansPregnancyPregnancy Trimester, FirstProspective StudiesRisk FactorsYoung AdultHigh risk pregnancyIUGRMaternal-fetal medicineMental healthPsychologyRisk assessmentSocial supportSocial work

Identifiers

PMID41146068
PMCPMC12560294

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.