ArticleBMC infectious diseases2025
Disease burden of HIV and its behavioral risks among adults aged 20-54 years in China and the Western Pacific Region from 1990 to 2021: an analysis based on the Global Burden of Disease Study 2021.
Article in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Epidemiological yield and cost-effectiveness of non-targeted community HIV screening in a low-prevalence district: a prospective quasi-experimental study.Frontiers in public health · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
backgroundThe HIV epidemic remains a significant public health concern among individuals aged 20–54 years. However, comprehensive studies evaluating trends in HIV-related health burdens and associated behavioral risks in China and the Western Pacific Region are limited.
methodsThis study utilizes data from the Global Burden of Diseases, Injuries, and Risk Factors Study 2021 to examine HIV burden indicators—including the age specific rates (ASR) for prevalence (ASPR), incidence (ASIR), mortality (ASMR) and DALYs (ASDR)—among individuals aged 20–54 years in China and the Western Pacific Region from 1990 to 2021. Long-term trends were analyzed using average annual percentage changes (AAPCs), while short-term trends were assessed through annual percentage changes (APCs). Furthermore, trends in HIV-related DALYs associated with behavioral risks were analyzed.
resultsIn China, ASPR increased by 751.27% (AAPC = 7.19, 95%CI: 7.02–7.35), ASIR by 232.26% (AAPC = 3.8, 95%CI: 2.62–4.99), ASMR by 1535.29% (AAPC = 9.07, 95%CI: 8.51–9.63), and ASDR by 1379.27% (AAPC = 8.72, 95%CI: 8.22–9.23). In the Western Pacific Region, ASPR increased by 1101.91% (AAPC = 8.34, 95%CI: 8.2–8.47), ASIR by 354.24% (AAPC = 4.68, 95%CI: 3.91–5.45), ASMR by 1241.67% (AAPC = 8.56, 95%CI: 8.05–9.08), and ASDR by 1135.86% (AAPC = 8.28, 95%CI: 7.83–8.73). Regarding the HIV-related DALYs rate attributable to behavioral risks, the corresponding rate for unsafe sex, intimate partner violence, and drug use showed a significant increase from 1990 to 2021 in China and the Western Pacific Region (all AAPC > 0, p < 0.05). Notably, the HIV burden was consistently higher in males than females in both regions, with most of gender disparities widening over time.
conclusionDespite significant progress in HIV/AIDS response, the burden remains substantial, with notable gender differences. Strengthened international cooperation, targeted prevention strategies, and expanded access to treatment are crucial to mitigating new HIV infections and improving health outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.