Evidence map›Paper›PMID 41146033›Full record

ArticleBMC cardiovascular disorders2025

Association between triglyceride glucose body mass index and the prognosis of patients with atrial fibrillation complicated with acute coronary syndrome: a prospective study.

Yijing Xin, Yimeng Wang, Yuyuan Shu, Hanyang Liang, Yanmin Yang, Ping Qing

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Article in BMC cardiovascular disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Yijing XinEmergency Center, State Key Laboratory of Cardiovascular Disease of China, National Center for Cardiovascular Diseases, National Clinical Research Center of Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China.
Yimeng WangEmergency Center, State Key Laboratory of Cardiovascular Disease of China, National Center for Cardiovascular Diseases, National Clinical Research Center of Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China.
Yuyuan ShuEmergency Center, State Key Laboratory of Cardiovascular Disease of China, National Center for Cardiovascular Diseases, National Clinical Research Center of Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China.
Hanyang LiangEmergency Center, State Key Laboratory of Cardiovascular Disease of China, National Center for Cardiovascular Diseases, National Clinical Research Center of Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China.
Yanmin YangEmergency Center, State Key Laboratory of Cardiovascular Disease of China, National Center for Cardiovascular Diseases, National Clinical Research Center of Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China. yangymfw@163.com.
Ping QingEmergency Center, State Key Laboratory of Cardiovascular Disease of China, National Center for Cardiovascular Diseases, National Clinical Research Center of Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100037, China. qing.ping@263.net.

Funding

High level Hospital Clinical Research Funds 2022-GSP-GG-26
6 · The paper itself

Abstract

backgroundThe triglyceride-glucose body mass index (TyG-BMI) is a reliable marker of insulin resistance and has been linked to cardiovascular outcomes. However, data on the relationship between TyG-BMI and prognosis in patients with atrial fibrillation (AF) complicated by acute coronary syndrome (ACS) are limited. This study aimed to evaluate the association between baseline TyG-BMI and prognosis in AF-ACS patients.

methodsWe conducted a single-center prospective analysis of 832 AF-ACS patients hospitalized at Fuwai Hospital from January 2017 to December 2019. The primary outcome was the incidence of major adverse cardio-cerebrovascular events (MACCEs) during the 1-year follow-up. Kaplan-Meier curves compared MACCE risk across four TyG-BMI quartiles. Cox proportional hazards regression and restricted cubic spline (RCS) analyses assessed the relationship between TyG-BMI and patient outcomes.

resultsThe mean age of participants was 68.15 ± 9.59 years, with 569 (68.39%) being male. Kaplan-Meier analysis showed significant differences in 1-year MACCE risk between the four groups. Cox regression revealed that patients in the lowest TyG-BMI quartile had a significantly higher 1-year MACCE risk. RCS analysis indicated a linear increase in MACCE risk with decreasing TyG-BMI.

conclusionTyG-BMI is closely associated with the prognosis of AF-ACS patients. Lower TyG-BMI is significantly linked to a higher risk of MACCEs in this population.

Indexed as

Acute Coronary SyndromeAtrial FibrillationBlood GlucoseBody Mass IndexTriglyceridesAgedBiomarkersChinaFemaleHumansInsulin ResistanceMaleMiddle AgedPredictive Value of TestsPrognosisProspective StudiesBiomarkersBlood GlucoseTriglyceridesAcute coronary syndromeAtrial fibrillationInsulin resistancePrognosisTriglyceride glucose-body mass index (TyG-BMI)

Identifiers

PMID41146033
PMCPMC12557995

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