Evidence map›Paper›PMID 41146026›Full record

Trial reportBMC primary care2025

Usefulness of the BRIEF-Multidimensional Prognostic Index (BRIEF-MPI) to identify older adults' healthcare needs to be addressed with a Personalized Prevention Program in general practice: preliminary data from the PrimaCare_P3 study.

Alberto Pilotto, Wanda Morganti, Emanuele Seminerio, Eleonora Lacorte, Carlo Custodero, Nicola Veronese, Peter Fielding, Carolina Massone, Paola Piscopo, Elisa Fabrizi and 9 more

Registry-linked trialAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in BMC primary care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06224556 (A Personalized Prevention Program), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06224556 narecruitingnot on this map

A Personalized Prevention Program (PPP) Based on the Comprehensive Geriatric Assessment (CGA) for the Prevention of Multidimensional Frailty Related to Non-communicable Chronic Diseases (NCDs) in Older People: a Practical Approach in Primary Care Setting

TypeinterventionalSponsorAlberto PilottoRan2024 to 2025Enrolled1,216ConditionsOlder People, Non-Communicable Chronic DiseasesArmsBrief-MPI assessment (based on the Comprehensive Geriatric Assessment), Personalized Prevention Program
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Alberto PilottoResearch, Development and Scientific Coordination Unit, National Reference & High Specialization Hospital, E.O. Galliera Hospitals, Genoa, Italy.
Wanda MorgantiResearch, Development and Scientific Coordination Unit, National Reference & High Specialization Hospital, E.O. Galliera Hospitals, Genoa, Italy. wanda.morganti@galliera.it.
Emanuele SeminerioResearch, Development and Scientific Coordination Unit, National Reference & High Specialization Hospital, E.O. Galliera Hospitals, Genoa, Italy.
Eleonora LacorteNational Center for Disease Prevention and Health Promotion, Italian National Institute of Health, Rome, Italy.
Carlo CustoderoDepartment of Interdisciplinary Medicine, "Aldo Moro" University of Bari, Bari, Italy.
Nicola VeroneseFaculty of Medicine, Saint Camillus International University of Health Sciences, Rome, Italy.
Peter FieldingResearch, Development and Scientific Coordination Unit, National Reference & High Specialization Hospital, E.O. Galliera Hospitals, Genoa, Italy.
Carolina MassoneResearch, Development and Scientific Coordination Unit, National Reference & High Specialization Hospital, E.O. Galliera Hospitals, Genoa, Italy.
Paola PiscopoNational Center for Disease Prevention and Health Promotion, Italian National Institute of Health, Rome, Italy.
Elisa FabriziNational Center for Disease Prevention and Health Promotion, Italian National Institute of Health, Rome, Italy.
Patrizia LorenziniNational Center for Disease Prevention and Health Promotion, Italian National Institute of Health, Rome, Italy.
Alberto MagniMedici Insieme Garda Valsabbia Società Cooperativa, Desenzano del Garda, Italy.
Gaetano PiccinocchiCOMEGEN Società Cooperativa Sociale, Naples, Italy.
Carlo IgnazziPolimedica Società Cooperativa, Putignano, Bari, Italy.
Lorenza BuscoMGCOOP Area 10 Leonardo Società Cooperativa, Florence, Italy.
Mario BarbagalloGeriatrics Unit, Department of Internal Medicine and Geriatrics, University of Palermo, Palermo, Italy.
Cesare MassoneResearch, Development and Scientific Coordination Unit, National Reference & High Specialization Hospital, E.O. Galliera Hospitals, Genoa, Italy.
Pierangelo Lora AprileItalian College of General Practitioners and Primary Care, Florence, Italy.
Nicola VanacoreNational Center for Disease Prevention and Health Promotion, Italian National Institute of Health, Rome, Italy.

Funding

European Union- Next Generation EU- NRRP M6C2- Investment 2.1 Enhancement and strengthening of biomedical research in the NHS PNRR-MAD-2022-12376781, CUP J33C22004060006
6 · The paper itself

Abstract

backgroundIn Europe around 40% of people aged ≥ 65 years are affected by multiple non-communicable chronic diseases (NCDs). The Comprehensive Geriatric Assessment (CGA) showed its usefulness in early identifying healthcare needs of older people with NCDs to develop a care plan to meet these needs. PrimaCare_P3 study aims at assessing healthcare needs of older people referring to their general practitioners (GPs) to plan a personalised prevention programme (PPP) based on the results of the CGA-based short version of the Multidimensional Prognostic Index (BRIEF-MPI).

methods612 participants with at least one NCDs were included in the intervention group (IG) by twenty GPs from four geographical areas. Functional, cognitive, nutritional, social and co-habitation conditions, co-morbidity, polytherapy, and vaccination status were assessed. Following the CGA-based BRIEF-MPI assessment, participants were provided with a PPP, consisting of targeted indications and interventions including prescribed specialistic examinations, if needed.

resultsPolytherapy and nutritional status were the most impaired domains with 59% of participants showing severe polypharmacy requiring a deprescribing strategy on GP's judgement while 25% of participants being malnourished or overweight/obese. Moreover, 22% of participants showed cognitive impairment requiring intervention, 18.5% were at risk of social isolation and/or loneliness, and 16.5% had some form of functional impairments in activities of daily living. Missing vaccinations according to the National Vaccination Prevention Plan (PNPV) were anti-influenza (34%), anti-COVID-19 (45%), anti-pneumococcus (74%), anti-herpes zoster (89%).

conclusionsThese data suggest that the CGA-based BRIEF-MPI assessment could effectively identify older adults' healthcare needs to be addressed with a PPP in general practice setting.

trial registrationRegistered on clinicaltrials.gov, NCT06224556, 05-01-2024.

Indexed as

General PracticeGeriatric AssessmentNeeds AssessmentNoncommunicable DiseasesAgedAged, 80 and overEuropeFemaleHumansMalePolypharmacyPrecision MedicinePrognosis

Identifiers

PMID41146026
PMCPMC12557916

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.