ArticleMedical physics2025
Dosimetric evaluation of unlaminated radiochromic films exposed to an Americium-241 source using measurements and Monte Carlo simulations.
Article in Medical physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
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4 authors.
Funding
Abstract
backgroundRadiochromic GafChromic film models are widely used in clinical settings for quality assurance during cancer treatment planning. Although these films are extensively studied in photon dosimetry, research on their application in α-particle dosimetry remains limited. With the growing use of α-particles in cancer therapy, it is important to establish film dosimetry protocols tailored to α-particles. Unlike photons, α-particles are charged, have a high linear energy transfer, and induce significantly greater biological damage, highlighting the need for specialized dosimetric approaches. PURPOSE: This study aimed to evaluate the response of various unlaminated GafChromic film models including EBT3, EBT-XD, and HD-V2, irradiated with an
methodsIn this study, unlaminated EBT3, EBT-XD, and HD-V2 film pieces were irradiated with an
resultsThe mean dose rates within a 1 mm diameter circular region of interest in the active layers of the three unlaminated GafChromic film models were determined to be 3.77 ± 0.002 Gy/min for EBT3, 4.04 ± 0.0022 Gy/min for EBT-XD, and 4.25 ± 0.0017 Gy/min for HD-V2. When the film material was changed to water, the dose rate was increased 14.3% for EBT3, 19.2% for EBT-XD, and 15.0% for HD-V2, with EBT3 showing the closest match to water-equivalence. Calibration curves for each film model were generated by fitting a power function to their responses. Refinements to the dose range were necessary to achieve an uncertainty below the 5% threshold. Among the models, HD-V2 required the most adjustments to its dose range and exhibited the highest levels of experimental, fit, and total uncertainties, along with the largest relative dose errors.
conclusionsThis study investigated α-particle dosimetry protocols for unlaminated EBT3, EBT-XD, and HD-V2 GafChromic film models using experimental irradiations and MC simulations. Although EBT3 and EBT-XD demonstrate strong potential for α-particle quality assurance in treatment planning, the HD-V2 film model requires further investigation before it can be recommended for this application.
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