ReviewCurrent atherosclerosis reports2025
Highlights of Cardiovascular Disease Prevention Studies Presented at the 2025 European Society of Cardiology Conference.
Review in Current atherosclerosis reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Highlights of Cardiovascular Disease Prevention Studies Presented at the 2025 American Heart Association Scientific Sessions.Current atherosclerosis reports · 2026Review
- The influence of parental educational involvement on learning engagement among first-year college students: the mediating effects of academic self-efficacy and professional identity.Frontiers in psychology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewThis review summarizes key findings from cardiovascular disease prevention studies presented at the 2025 European Society of Cardiology (ESC) Conference. It highlights trials on novel therapies, vaccination, blood pressure management, and the use of technology and risk scores to guide treatment. RECENT
findingsThe CONFIDENCE trial showed that a combination of finerenone and empagliflozin significantly reduced the urine albumin-creatinine ratio in patients with type 2 diabetes mellitus and chronic kidney disease. The DANFLU-2 trial found that the high-dose influenza vaccine was associated with fewer cardio-respiratory hospitalizations in older adults compared to the standard dose. The RETREAT FRAIL trial demonstrated that tapering antihypertensive medications in frail, elderly patients safely reduced pill burden without increasing all-cause mortality and adverse cardiovascular (CV) and non-CV outcomes. In diagnostics, the AI-Gatekeeper trial showed an AI tool reduced unnecessary advanced imaging for coronary artery disease (CAD) by 76%, lowering costs without compromising safety. The CAC CV-PREVITAL trial found that adding a coronary artery calcium score to standard risk assessment improved blood pressure control. The REBOOT-CNIC trial challenged a paradigm, showing that beta-blockers provided no significant benefit in post-myocardial infarction patients without reduced ejection fraction. A Post hoc analysis of SURMOUNT-5 found that tirzepatide offers a more pronounced long-term reduction in cardiovascular disease risk compared with semaglutide for adults with obesity and without diabetes. The NATURE-Legacy trial provided compelling evidence for the "legacy benefit" of early, modest reductions in LDL-C and blood pressure. The AIMHY-INFORM Dual Therapy Arm highlighted ethnic differences in blood pressure responses to dual therapy, while the OUTREACH trial demonstrated that providing feedback to patients on antihypertensive adherence using urine testing improved medication adherence. The 2025 ESC Conference featured several impactful studies on cardiovascular disease prevention, highlighting the importance of a multifaceted approach that incorporates the strategic integration of AI and a deeper understanding of patient-specific factors. As cardiovascular disease remains the leading global cause of death, these findings underscore the necessity of moving toward more personalized, evidence-based, and technologically-driven preventive care to improve patient outcomes and reduce the overall disease burden.
Indexed as
Identifiers
41145911What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.