Evidence map›Paper›PMID 41145588›Full record

ArticleScientific reports2025

Actin cytoskeleton dynamics affect replication of human Metapneumovirus.

Pamela Elizabeth Rodríguez, Pedro Ignacio Gil, Jorge Augusto Cámara, Alicia Cámara, María Gabriela Paglini

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Pamela Elizabeth Rodríguez *Laboratory of Influenza and other Respiratory Viruses, Virology Institute "Dr. J. M. Vanella", Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Córdoba, Córdoba, Argentina.ORCID http://orcid.org/0000-0003-3827-3760
Pedro Ignacio Gil *Laboratory of Cell Biology of Viral Infection, Virology Institute "Dr. J. M. Vanella". Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Enfermera Gordillo s/n. Ciudad Universitaria, Córdoba, Córdoba, 5000, Argentina.ORCID http://orcid.org/0000-0002-5444-063X
Jorge Augusto CámaraLaboratory of Influenza and other Respiratory Viruses, Virology Institute "Dr. J. M. Vanella", Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Córdoba, Córdoba, Argentina.ORCID http://orcid.org/0000-0002-5072-2795
Alicia CámaraLaboratory of Influenza and other Respiratory Viruses, Virology Institute "Dr. J. M. Vanella", Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Córdoba, Córdoba, Argentina.ORCID http://orcid.org/0000-0003-3988-2664
María Gabriela PagliniLaboratory of Cell Biology of Viral Infection, Virology Institute "Dr. J. M. Vanella". Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Enfermera Gordillo s/n. Ciudad Universitaria, Córdoba, Córdoba, 5000, Argentina. gpaglini@immf.uncor.edu.ORCID http://orcid.org/0000-0002-2565-8699

Funding

Fundación Alberto J. Roemmers 2017-2019Fundación Alberto J. Roemmers 2018-2020Secretaría de Ciencia y Tecnología, Universidad Nacional de Córdoba, Argentina SECYT-Consolidar-C Nº 33620180100091CBSecretaría de Ciencia y Tecnología, Universidad Nacional de Córdoba, Argentina (SECYT- Consolidar-I Nº 336 20180100191CB
6 · The paper itself

Abstract

Human Metapneumovirus (hMPV) is a leading cause of viral respiratory infection with clinical and epidemiological relevance in pediatric, immunocompromised, and elderly populations. Little is known about hMPV in vitro replication processes and their relationship with cellular structures such as the cytoskeleton. Our goal was to evaluate the role of the actin cytoskeleton in hMPV replication at different stages of viral growth. hMPV was isolated in Vero cells from a clinical sample and identified as A

Indexed as

Actin CytoskeletonMetapneumovirusParamyxoviridae InfectionsVirus ReplicationAnimalsChlorocebus aethiopsHumansVero CellsActin filamentsCytochalasin DReplication cycleRespiratory disease.Virus isolation

Identifiers

PMID41145588
PMCPMC12559302

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.