ArticleScientific reports2025
Extraction and characterization of antibacterial marine polysaccharide K-Carrageenan from Kappaphycus alvarezii against multidrug-resistant wound associated bacteria.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Effect of dietary carrageenan supplementation on growth performance, digestive enzyme and antioxidant enzyme activity, immune gene expression, and capacity against S. agalactiae of Nile tilapia (Oreochromis niloticus).Fish physiology and biochemistry · 2026Article
- Novel Ternary Biopolymer Films Incorporating Amygdalin: FTIR, TG, and In Vitro Evaluation on Model Bacteria.Materials (Basel, Switzerland) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Antimicrobial resistance (AMR)-related diseases have ruined the lives of many people and the multidrug-resistant bacterial infections have a key role in the mortality associated with antimicrobial resistance (AMR). The focus was shifted to natural resources for the development of antimicrobial compounds in order to overcome this resistance. In this study K-Carrageenan was extracted from Kappaphycus alvarezii and characterized by the Fourier transform infrared (FTIR), Gas chromatography mass spectrometry (GC-MS), Liquid chromatography mass spectrum (LC-MS) and Nuclear Magnetic Resonance (H-NMR) analysis. The antibacterial property of carrageenan was tested using the Minimum Inhibitory Concentration and the bacterial cell growth rate. The results showed higher antibacterial activity of K-Carrageenan against S. aureus, E. coli, P. aeruginosa, P. vulgaris, and V. parahaemolyticus. Well diffusion method, growth curve studies, anti-biofilm studies were done in K-Carrageenan. Intracellular protein molecules and nucleic acid leakage confirmed that 100 µg/mL of K-Carrageenan increase membrane permeability, leading to cell death. At a concentration of 100 µg/mL of K-Carrageenan was non-cytotoxic to RBCs cells and promoted antibacterial and antibiofilm properties against the wound pathogens. From this study, these results determine the strong potential of K-Carrageenan treating MDR bacteria-infected chronic wounds.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.