Evidence map›Paper›PMID 41145447›Full record

ArticleNature communications2025

Stage-specific roles of clonally expanded CD8

Masaki Ohyagi, Minako Ito, Mana Iizuka-Koga, Setsuko Mise-Omata, Akihiko Yoshimura

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
  2. Review
  3. T Cell Thoughts.Immunological reviews · 2026
    Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. Senescence of T cells and organ aging.Inflammation and regeneration · 2026
    Review
  17. Review
  18. Review
  19. Review
  20. Interleukin-6, CD8Frontiers in aging neuroscience · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Masaki OhyagiDivision of Molecular Pathology, Research Institute for Biomedical Sciences, Tokyo University of Science, Chiba, Japan. ohyanuro@gmail.com.ORCID http://orcid.org/0000-0002-6009-450X
Minako ItoDivision of Allergy and Immunology, Medical Institute of Bioregulation Kyushu University, Fukuoka, Japan.ORCID http://orcid.org/0000-0002-5809-472X
Mana Iizuka-KogaDivision of Molecular Pathology, Research Institute for Biomedical Sciences, Tokyo University of Science, Chiba, Japan.
Setsuko Mise-OmataDivision of Molecular Pathology, Research Institute for Biomedical Sciences, Tokyo University of Science, Chiba, Japan.
Akihiko YoshimuraDivision of Molecular Pathology, Research Institute for Biomedical Sciences, Tokyo University of Science, Chiba, Japan. yoshimura@keio.jp.

Funding

MEXT | Japan Society for the Promotion of Science (JSPS) 20K22789MEXT | Japan Society for the Promotion of Science (JSPS) 21K15473MEXT | Japan Society for the Promotion of Science (JSPS) 23KJ1876MEXT | Japan Society for the Promotion of Science (JSPS) 25K18841Takeda Science Foundation 2023049173
6 · The paper itself

Abstract

Clonally expanded CD8

Indexed as

Alzheimer DiseaseCD8-Positive T-LymphocytesPlaque, AmyloidAmyloid beta-PeptidesAnimalsBrainChemokine CCL5Disease Models, AnimalFemaleHumansMaleMiceMice, Inbred C57BLMice, TransgenicMicrogliaReceptors, Antigen, T-CellAmyloid beta-PeptidesCcl5 protein, mouseCCR5 protein, mouseChemokine CCL5Receptors, Antigen, T-CellReceptors, CCR5

Identifiers

PMID41145447
PMCPMC12559718

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.