ArticleYonsei medical journal2025
Antenatally Diagnosed Ventriculomegaly: Postnatal Clinical Course and Neurodevelopmental Insights.
Article in Yonsei medical journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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12 authors.
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Abstract
purposeAntenatal ventriculomegaly (VM), a prevalent fetal central nervous system (CNS) abnormality, ranges from isolated VM to VM with additional CNS abnormalities. This study aimed to analyze postnatal diagnoses and clinical outcomes of patients with antenatal VM to identify key prenatal factors. MATERIALS AND
methodsNeonates born at ≥35 weeks of gestation between 2010 and 2022 with antenatal VM were retrospectively reviewed. Patients were categorized as VM with other CNS abnormalities (group A, n=95), isolated VM (group B, n=40), and resolved VM (group C, n=80). CNS abnormalities identified postnatally but not prenatally were classified as group A2 (n=38). Imaging findings, clinical features, and 2-year neurodevelopmental outcomes were compared.
resultsGroup A showed higher rates of bilateral VM (78.9% vs. 50.0% vs. 27.5%,
conclusionLarger initial ventricle size in antenatal VM was associated with poorer neurodevelopmental outcomes. Normal antenatal findings can obscure postnatal CNS abnormalities. Advanced imaging and postnatal evaluation are essential for timely diagnosis and perinatal counseling and management.
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