Evidence map›Paper›PMID 41145158›Full record

ArticleAmerican journal on intellectual and developmental disabilities2025

FMR1 Premutation Carrier Mothers' Daily Negative Affect and Cortisol: Probing the Impacts of Stress Exposure, Coping Style, and CGG Repeats.

Leann Smith DaWalt, Jinkuk Hong, Catherine Rogers Gaspar, Ashley Woodman, Elizabeth M Berry-Kravis, Marsha R Mailick

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal on intellectual and developmental disabilities, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Cognitive dysfunction in women with theJournal of Alzheimer's disease : JAD · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Leann Smith DaWaltLeann Smith DaWalt, Jinkuk Hong, and Catherine Rogers Gaspar, Waisman Center, University of Wisconsin-Madison; Ashley Woodman, University of Massachusetts-Amherst; Elizabeth M. Berry-Kravis, Rush University Medical Center; and Marsha R. Mailick, Waisman Center, University of Wisconsin-Madison.
Jinkuk HongLeann Smith DaWalt, Jinkuk Hong, and Catherine Rogers Gaspar, Waisman Center, University of Wisconsin-Madison; Ashley Woodman, University of Massachusetts-Amherst; Elizabeth M. Berry-Kravis, Rush University Medical Center; and Marsha R. Mailick, Waisman Center, University of Wisconsin-Madison.
Catherine Rogers GasparLeann Smith DaWalt, Jinkuk Hong, and Catherine Rogers Gaspar, Waisman Center, University of Wisconsin-Madison; Ashley Woodman, University of Massachusetts-Amherst; Elizabeth M. Berry-Kravis, Rush University Medical Center; and Marsha R. Mailick, Waisman Center, University of Wisconsin-Madison.
Ashley WoodmanLeann Smith DaWalt, Jinkuk Hong, and Catherine Rogers Gaspar, Waisman Center, University of Wisconsin-Madison; Ashley Woodman, University of Massachusetts-Amherst; Elizabeth M. Berry-Kravis, Rush University Medical Center; and Marsha R. Mailick, Waisman Center, University of Wisconsin-Madison.
Elizabeth M Berry-KravisLeann Smith DaWalt, Jinkuk Hong, and Catherine Rogers Gaspar, Waisman Center, University of Wisconsin-Madison; Ashley Woodman, University of Massachusetts-Amherst; Elizabeth M. Berry-Kravis, Rush University Medical Center; and Marsha R. Mailick, Waisman Center, University of Wisconsin-Madison.
Marsha R MailickLeann Smith DaWalt, Jinkuk Hong, and Catherine Rogers Gaspar, Waisman Center, University of Wisconsin-Madison; Ashley Woodman, University of Massachusetts-Amherst; Elizabeth M. Berry-Kravis, Rush University Medical Center; and Marsha R. Mailick, Waisman Center, University of Wisconsin-Madison.

Funding

Waisman Center Intellectual and Developmental Disabilities Research CenterP50HD105353 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI Brittany Gail Travers · 2021 to 2026
$8.5M
FMR1 Premutation Phenotypes in Population-Based & Clinically-Ascertained SamplesR01HD082110 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI Leann Smith DaWalt, MARSHA RUTH MAILICK · 2015 to 2026
$5.1M
NICHD NIH HHS P50 HD105353NICHD NIH HHS R01 HD082110
6 · The paper itself

Abstract

This study utilized a daily diary methodology to investigate negative affect and cortisol secretion of mothers of adolescents and adults with fragile X syndrome (n = 104). We investigated whether coping style moderated the effects of child behavior problems on daily stress responses for these mothers and whether mothers with varying numbers of CGG repeats differed in the extent to which their coping style impacted daily outcomes. Results indicated that high levels of problem-focused coping buffered the effects of behavior problems on mothers' negative affect and cortisol secretion. There was a significant interaction between CGG repeat group and coping in predicting negative affect; mothers with midrange CGG repeats were less likely to benefit from coping than those who had fewer repeats.

Indexed as

Adaptation, PsychologicalAffectFragile X Messenger Ribonucleoprotein 1Fragile X SyndromeHydrocortisoneMothersStress, PsychologicalAdolescentAdultChildFemaleHumansMaleMiddle AgedYoung AdultFMR1 protein, humanFragile X Messenger Ribonucleoprotein 1Hydrocortisonebehavior problemscopingcortisoldaily diaryfragile X syndromenegative affectpremutation

Identifiers

PMID41145158
PMCPMC13092322

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.