Evidence map›Paper›PMID 41145015›Full record

ReviewCurrent opinion in psychology2026

Potential harm from universal school-based mental health interventions: Candidate mechanisms and future directions.

Lucy Foulkes, Carolina Guzman Holst, Jack L Andrews

Abstract readReview
In one paragraph

Review in Current opinion in psychology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lucy FoulkesDepartment of Experimental Psychology, University of Oxford, Life and Mind Building, South Parks Road, Oxford, OX1 3PS, UK. Electronic address: lucy.foulkes@psych.ox.ac.uk.
Carolina Guzman HolstDepartment of Experimental Psychology, University of Oxford, Life and Mind Building, South Parks Road, Oxford, OX1 3PS, UK.
Jack L AndrewsDepartment of Experimental Psychology, University of Oxford, Life and Mind Building, South Parks Road, Oxford, OX1 3PS, UK.

Funding

Wellcome Trust 227640
6 · The paper itself

Abstract

Universal school-based mental health interventions involve lessons delivered to whole classes of young people irrespective of need, with the overall aim of improving mental health literacy, preventing mental health problems and/or reducing those that have already started. A number of high-quality trials show that universal interventions can have a range of negative effects, with participants in the intervention group experiencing worsening mental health or other negative outcomes. In this review, we summarise what we know so far about these negative effects, which we refer to as 'potential harm'. Two important questions remain poorly understood. First, the mechanisms driving potential harm are unknown, including whether negative effects are driven by reporting phenomena, the content of the intervention itself, or both. Second, individual differences in susceptibility to these effects is unclear. In the second half of the paper, we explore whether further universal trials should be run and argue that, if they are, the crucial issue of negative effects must be considered at all stages. In particular, we recommend that trials be designed in such a way to test mechanisms and individual differences in response. Information can then be provided to schools and policymakers about why young people might respond in different ways to an intervention, and how to support vulnerable students. Ultimately, this will lead to more effective and less harmful interventions for everyone.

Indexed as

Mental DisordersMental HealthSchool Mental Health ServicesAdolescentHumans

Identifiers

PMID41145015
PMCPMC7618766

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.