Evidence map›Paper›PMID 41144737›Full record

ArticleThe Milbank quarterly2025

How Did Medicaid's 1115 Substance Use Disorder Waivers Increase Medication Treatment for Opioid Use Disorder? Evidence From Eight Waiver States.

Stephan R Lindner, Jennifer Hall, Brynna Manibusan, Jordan Byers, Kyle Hart, Andrea Baron, Dennis McCARTY, K John McCONNELL, Deborah J Cohen

Abstract read
In one paragraph

Article in The Milbank quarterly, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Stephan R LindnerCenter for Health Systems Effectiveness, Oregon Health & Science University.ORCID 0000-0002-9577-6287
Jennifer HallOregon Health & Science University.
Brynna ManibusanCenter for Health Systems Effectiveness, Oregon Health & Science University.
Jordan ByersOregon Health & Science University.
Kyle HartCenter for Health Systems Effectiveness, Oregon Health & Science University.
Andrea BaronBoulder Care.
Dennis McCARTYCenter for Health Systems Effectiveness, Oregon Health & Science University.
K John McCONNELLCenter for Health Systems Effectiveness, Oregon Health & Science University.ORCID 0000-0003-1280-3196
Deborah J CohenOregon Health & Science University.

Funding

The Effects of States' Substance Use Waivers on Healthcare Utilization and Opioid-related Overdoses Among Medicaid Enrollees with Opioid Use DisorderR01DA052388 · NIDA · OREGON HEALTH & SCIENCE UNIVERSITY · PI LINDNER, STEPHAN REINHARD · 2021 to 2024
$2.5M
High Performance Computing and Machine Learning Infrastructure for Oregon Life SciencesS10OD034224 · OD · OREGON HEALTH & SCIENCE UNIVERSITY · PI ELLROTT, KYLE · 2023 to 2023
$2.0M
National Institute on Drug Abuse R01DA052388NIDA NIH HHS R01 DA052388NIH HHS S10 OD034224
6 · The paper itself

Abstract

Policy Points States can use substance use disorder waivers to improve their program, but findings regarding the effects of these waivers on opioid use disorder medication treatment have shown mixed results. This study used a mixed-methods design to identify strategies that states undertook as part of their waiver and that may have led to increases in the use of methadone or buprenorphine. For methadone, adding coverage, increasing reimbursement rates, and engaging providers and managed care organizations may be effective strategies to increase the use of this medication. In contrast, no consistent strategies were identified for buprenorphine. CONTEXT: Starting in 2015, states could apply for section 1115 substance use disorder (SUD) waivers to strengthen their continuum of care for treatment of opioid use disorder (OUD). Prior research found substantial variation in changes to medication use for OUD associated with waiver implementation. The objective of this study was to identify strategies that states undertook as part of their waivers that were associated with increases in methadone and buprenorphine treatment in eight waiver states (Indiana, Louisiana, New Hampshire, New Jersey, Pennsylvania, Virginia, Washington, and West Virginia).

methodsIn this mixed-methods study, we combined quantitative difference-in-differences analyses of 2016-2021 Medicaid data with qualitative analyses of states' waiver application documents (N = 8) and interviews (N = 23) with individuals involved in waiver implementation.

findingsSUD waiver implementation was associated with increased use of methadone in Virginia (estimate: 15.4 percentage points [pp]; p < 0.001), Indiana (estimate: 13.2 pp; p < 0.001), West Virginia (estimate: 9.5 pp; p < 0.001), Louisiana (estimate: 7.2 pp; p < 0.001), and New Jersey (estimate: 4.2 pp; p < 0.05). Qualitative information indicated that these states used a variety of strategies, including adding coverage, increasing reimbursement rates, and engaging providers and managed care organizations. By contrast, we observed limited or no strategies to increase the use of methadone in the other states. SUD waiver implementation was associated with increased buprenorphine prescribing in Pennsylvania (estimate: 5.2 pp; p < 0.001), Washington (estimate: 5.2 pp; p < 0.001), New Hampshire (estimate: 4.4 pp; p < 0.01), Louisiana (estimate: 4.2 pp; p < 0.01), and Indiana (estimate: 4.2 pp; p < 0.01). Qualitative analyses suggested that states with and without increases in this outcome implemented similar changes (e.g., education and training activities).

conclusionsQualitative findings helped explain state-level variation in methadone treatment following SUD waiver implementation but not for buprenorphine. Strategies identified in higher-performing states may offer useful insights for other states aiming to expand access to methadone for OUD.

Indexed as

BuprenorphineMedicaidMethadoneOpiate Substitution TreatmentOpioid-Related DisordersHumansUnited StatesBuprenorphineMethadone1115 waiversMedicaidmixed‐methodsopioid use disorder

Identifiers

PMID41144737
PMCPMC12668779

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.